Complex cytogenetic changes in Ph-negative chronic myelogenous leukemia

Tian You Wang, Azra Raza, Yao Shan Fan, Sheila N. Jani Sait, Jeffrey Kirschner, Avery A. Sandberg

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A Ph-negative chronic myelogenous leukemia (CML) with t(3;7)(q21;q32), t(4;9)(q21;q34), and del(8)(q22) is reported. This case is rather unusual for Ph-negative CML in being associated with complex chromosome changes. The patient was diagnosed as in the accelerated phase of CML. It will be important to study this malignant disorder in detail cytogenetically and molecularly in order to ascertain its nature and place among the myeloproliferative disorders.

Original languageEnglish (US)
Pages (from-to)241-245
Number of pages5
JournalCancer Genetics and Cytogenetics
Issue number2
StatePublished - Apr 1988
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research


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