Complex cytogenetic changes in Ph-negative chronic myelogenous leukemia

Tian You Wang, Azra Raza, Yao-Shan Fan, Sheila N. Jani Sait, Jeffrey Kirschner, Avery A. Sandberg

Research output: Contribution to journalArticle

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Abstract

A Ph-negative chronic myelogenous leukemia (CML) with t(3;7)(q21;q32), t(4;9)(q21;q34), and del(8)(q22) is reported. This case is rather unusual for Ph-negative CML in being associated with complex chromosome changes. The patient was diagnosed as in the accelerated phase of CML. It will be important to study this malignant disorder in detail cytogenetically and molecularly in order to ascertain its nature and place among the myeloproliferative disorders.

Original languageEnglish
Pages (from-to)241-245
Number of pages5
JournalCancer Genetics and Cytogenetics
Volume31
Issue number2
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

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Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Cytogenetics
Leukemia, Myeloid, Chronic Phase
Myeloproliferative Disorders
Chromosomes

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

Cite this

Complex cytogenetic changes in Ph-negative chronic myelogenous leukemia. / Wang, Tian You; Raza, Azra; Fan, Yao-Shan; Jani Sait, Sheila N.; Kirschner, Jeffrey; Sandberg, Avery A.

In: Cancer Genetics and Cytogenetics, Vol. 31, No. 2, 01.01.1988, p. 241-245.

Research output: Contribution to journalArticle

Wang, Tian You ; Raza, Azra ; Fan, Yao-Shan ; Jani Sait, Sheila N. ; Kirschner, Jeffrey ; Sandberg, Avery A. / Complex cytogenetic changes in Ph-negative chronic myelogenous leukemia. In: Cancer Genetics and Cytogenetics. 1988 ; Vol. 31, No. 2. pp. 241-245.
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