Complete androgen insensitivity syndrome

Long-term medical, surgical, and psychosexual outcome

Amy B. Wisniewski, Claude J. Migeon, Heino F L Meyer-Bahlburg, John P. Gearhart, Gary Berkovitz, Terry R. Brown, John Money

Research output: Contribution to journalArticle

247 Citations (Scopus)

Abstract

Controversy concerning the most appropriate treatment guidelines for intersex children currently exists. This is due to a lack of long-term information regarding medical, surgical, and psychosexual outcome in affected adults. We have assessed by questionnaire and medical examination the physical and psychosexual status of 14 women with documented complete androgen insensitivity syndrome (CAIS). We have also determined participant knowledge of CAIS as well as opinion of medical and surgical treatment. As a whole, secondary sexual development of these women was satisfactory, as judged by both participants and physicians. In general, most women were satisfied with their psychosexual development and sexual function. Factors reported to contribute to dissatisfaction were sexual abuse in one case and marked obesity in another. All of the women who participated were satisfied with having been raised as females, and none desired a gender reassignment. Although not perfect, the medical, surgical, and psychosexual outcomes for women with CAIS were satisfactory; however, specific ways for improving long-term treatment of this population were identified.

Original languageEnglish
Pages (from-to)2664-2669
Number of pages6
JournalJournal of Clinical Endocrinology and Metabolism
Volume85
Issue number8
DOIs
StatePublished - Dec 1 2000

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Androgen-Insensitivity Syndrome
Androgens
Psychosexual Development
Sexual Development
Women's Rights
Sex Offenses
Physical Examination
Therapeutics
Obesity
Guidelines
Physicians
Population

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

Wisniewski, A. B., Migeon, C. J., Meyer-Bahlburg, H. F. L., Gearhart, J. P., Berkovitz, G., Brown, T. R., & Money, J. (2000). Complete androgen insensitivity syndrome: Long-term medical, surgical, and psychosexual outcome. Journal of Clinical Endocrinology and Metabolism, 85(8), 2664-2669. https://doi.org/10.1210/jc.85.8.2664

Complete androgen insensitivity syndrome : Long-term medical, surgical, and psychosexual outcome. / Wisniewski, Amy B.; Migeon, Claude J.; Meyer-Bahlburg, Heino F L; Gearhart, John P.; Berkovitz, Gary; Brown, Terry R.; Money, John.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 85, No. 8, 01.12.2000, p. 2664-2669.

Research output: Contribution to journalArticle

Wisniewski, Amy B. ; Migeon, Claude J. ; Meyer-Bahlburg, Heino F L ; Gearhart, John P. ; Berkovitz, Gary ; Brown, Terry R. ; Money, John. / Complete androgen insensitivity syndrome : Long-term medical, surgical, and psychosexual outcome. In: Journal of Clinical Endocrinology and Metabolism. 2000 ; Vol. 85, No. 8. pp. 2664-2669.
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