Compensation for spin-lock artifacts using an off-resonance rotary echo in T1ρoff-weighted imaging

Walter R.T. Witschey, Arijitt Borthakur, Mark A. Elliott, Eric Mellon, Sampreet Niyogi, Chenyang Wang, Ravinder Reddy

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


The origin of image artifacts in an off-resonance spin-locking experiment is shown to be imperfections in the excitation flip angle. A pulse sequence for off-resonance spin locking is implemented that compensates for imperfections in the excitation flip angle through an off-resonance rotary echo. The off-resonance rotary echo alternates the frequency offset and phase of the RF transmitter during two spin-locking pulses of equal duration. The underlying theory is detailed, and MR images demonstrate the effectiveness of the technique in agarose gel phantoms and in in vivo human brain at 3T.

Original languageEnglish (US)
Pages (from-to)2-7
Number of pages6
JournalMagnetic Resonance in Medicine
Issue number1
StatePublished - Jan 2007
Externally publishedYes


  • Off-resonance T
  • Rotary echo
  • Spin locking
  • T relaxation
  • T-weighted imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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