Comparisons of multiple automated anatomy-based image-guidance methods for patient setup before head/neck external beam radiotherapy

Nesrin Dogan, Shiyu Song, Habeeb Saleh, Jian Wu, Martin J. Murphy

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The purpose was to assess the variability in automated translational head/neck setup corrections computed from several different imaging modalities and rigid registration methods using patient anatomy. Shifts were calculated using three commercial and one in-house automated rigid registration methods for nine head/neck patients who were imaged with three different image-guidance systems. The mean difference between the daily isocenter shifts determined by the four methods ranged from 2.8 to 12.5 mm for all of the test cases. These differences are much greater than the variability observed for a rigid imaging phantom. Image-guided setup procedures have an uncertainty that depends on the imaging modality, the registration algorithm, the image resolution and the image content. In the absence of an absolute ground truth, the variation in the shifts calculated by several different methods provides a useful estimate of that uncertainty.

Original languageEnglish (US)
Pages (from-to)76-85
Number of pages10
JournalJournal of applied clinical medical physics
Volume12
Issue number1
DOIs
StatePublished - 2011
Externally publishedYes

Keywords

  • Head/neck radiotherapy
  • Image registration
  • Image-guided setup
  • Registration error
  • Setup uncertainty

ASJC Scopus subject areas

  • Radiation
  • Instrumentation
  • Radiology Nuclear Medicine and imaging

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