Abstract
BACKGROUND AND OBJECTIVE: To identify a needle to improve intravitreal dexamethasone implant administration by evaluating ease of ocular tissue penetration and glide force, key characteristics of needle performance. MATERIALS AND METHODS: Two custom-applicator needles coated with distinct lubricants (needles A and B) and the original dexamethasone implant needle were evaluated by five retina specialists. Ex vivo porcine eyes were injected, and a visual analog scale was used in ratings. RESULTS: Ease of ocular tissue penetration and glide force of needle B were rated significantly higher than that of the original applicator needle (P < .001), but there were no significant differences for needle A. Lot to lot, needle B was not significantly different in penetration and glide, whereas a significant difference was observed for penetration of needle A (P = .043). CONCLUSION : Needle design and lubricant appear to facilitate penetration and reduce glide force when administering dexamethasone intravitreal implants. Minimal lot-to-lot variation should be considered in needle choice.
| Original language | English |
|---|---|
| Pages (from-to) | 430-435 |
| Number of pages | 6 |
| Journal | Ophthalmic Surgery Lasers and Imaging Retina |
| Volume | 45 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 2014 |
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ASJC Scopus subject areas
- Ophthalmology
- Surgery
Cite this
Comparison of the tissue penetration and glide force of 22-gauge thin-wall needles for intravitreal implant administration. / Bakri, Sophie J.; Boyer, David S.; Albini, Thomas A; Holekamp, Nancy M.; Ferrone, Philip J.; Bhagat, Rahul; Novakovic, Zoran.
In: Ophthalmic Surgery Lasers and Imaging Retina, Vol. 45, No. 5, 01.01.2014, p. 430-435.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of the tissue penetration and glide force of 22-gauge thin-wall needles for intravitreal implant administration
AU - Bakri, Sophie J.
AU - Boyer, David S.
AU - Albini, Thomas A
AU - Holekamp, Nancy M.
AU - Ferrone, Philip J.
AU - Bhagat, Rahul
AU - Novakovic, Zoran
PY - 2014/1/1
Y1 - 2014/1/1
N2 - BACKGROUND AND OBJECTIVE: To identify a needle to improve intravitreal dexamethasone implant administration by evaluating ease of ocular tissue penetration and glide force, key characteristics of needle performance. MATERIALS AND METHODS: Two custom-applicator needles coated with distinct lubricants (needles A and B) and the original dexamethasone implant needle were evaluated by five retina specialists. Ex vivo porcine eyes were injected, and a visual analog scale was used in ratings. RESULTS: Ease of ocular tissue penetration and glide force of needle B were rated significantly higher than that of the original applicator needle (P < .001), but there were no significant differences for needle A. Lot to lot, needle B was not significantly different in penetration and glide, whereas a significant difference was observed for penetration of needle A (P = .043). CONCLUSION : Needle design and lubricant appear to facilitate penetration and reduce glide force when administering dexamethasone intravitreal implants. Minimal lot-to-lot variation should be considered in needle choice.
AB - BACKGROUND AND OBJECTIVE: To identify a needle to improve intravitreal dexamethasone implant administration by evaluating ease of ocular tissue penetration and glide force, key characteristics of needle performance. MATERIALS AND METHODS: Two custom-applicator needles coated with distinct lubricants (needles A and B) and the original dexamethasone implant needle were evaluated by five retina specialists. Ex vivo porcine eyes were injected, and a visual analog scale was used in ratings. RESULTS: Ease of ocular tissue penetration and glide force of needle B were rated significantly higher than that of the original applicator needle (P < .001), but there were no significant differences for needle A. Lot to lot, needle B was not significantly different in penetration and glide, whereas a significant difference was observed for penetration of needle A (P = .043). CONCLUSION : Needle design and lubricant appear to facilitate penetration and reduce glide force when administering dexamethasone intravitreal implants. Minimal lot-to-lot variation should be considered in needle choice.
UR - http://www.scopus.com/inward/record.url?scp=84911370051&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84911370051&partnerID=8YFLogxK
U2 - 10.3928/23258160-20140909-02
DO - 10.3928/23258160-20140909-02
M3 - Article
C2 - 25230401
AN - SCOPUS:84911370051
VL - 45
SP - 430
EP - 435
JO - Ophthalmic Surgery Lasers and Imaging Retina
JF - Ophthalmic Surgery Lasers and Imaging Retina
SN - 2325-8160
IS - 5
ER -