Comparison of the auditory-evoked brainstem response wave I to distortion-product otoacoustic emissions resulting from changes to inner ear blood flow

Fred F Telischi, Mom Thierry, Mark Agrama, Barden B. Stagner, Ozcan Ozdamar, Andres Bustillo, Glen K. Martin

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objective/Hypothesis: Examine and compare in detail the time courses of the auditory brainstem response (ABR) wave I amplitude and latency to the distortion-product otoacoustic emission (DPOAE) amplitude and phase measured in the rabbit model following deliberate obstruction of cochlear blood flow (CBF). Methods: Using a posterior fossa craniotomy in five rabbits, the internal auditory artery (IAA) was compressed with a probe. ABR and otoacoustic emission were continuously monitored before, during, and after the compressions. Results: ABR wave I amplitudes demonstrated measurable decreases at a mean of 28.3 s after IAA compression, whereas DPOAE amplitudes decreased after a mean of 14.8 s. Wave I latencies began to increase at a mean of 18.3 s after occlusion, while DPOAE phase measures changed after a mean of only 4.8 s following IAA compression. The time-course patterns were similar for the amplitudes of both ABR wave I and DPOAE. Conclusions: ABR wave I amplitude follows a similar, though delayed (by approximately 10 s) time-course pattern to that of the DPOAE following IAA compression. The implication of these findings for intraoperative auditory monitoring is that changes in many currently employed measures will lag actual surgically induced alterations in CBF by at least 20 to 30 s.

Original languageEnglish
Pages (from-to)186-191
Number of pages6
JournalLaryngoscope
Volume109
Issue number2 I
DOIs
StatePublished - Feb 1 1999

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Brain Stem Auditory Evoked Potentials
Inner Ear
Arteries
Cochlea
Rabbits
Intraoperative Monitoring
Craniotomy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Comparison of the auditory-evoked brainstem response wave I to distortion-product otoacoustic emissions resulting from changes to inner ear blood flow. / Telischi, Fred F; Thierry, Mom; Agrama, Mark; Stagner, Barden B.; Ozdamar, Ozcan; Bustillo, Andres; Martin, Glen K.

In: Laryngoscope, Vol. 109, No. 2 I, 01.02.1999, p. 186-191.

Research output: Contribution to journalArticle

Telischi, Fred F ; Thierry, Mom ; Agrama, Mark ; Stagner, Barden B. ; Ozdamar, Ozcan ; Bustillo, Andres ; Martin, Glen K. / Comparison of the auditory-evoked brainstem response wave I to distortion-product otoacoustic emissions resulting from changes to inner ear blood flow. In: Laryngoscope. 1999 ; Vol. 109, No. 2 I. pp. 186-191.
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