Comparison of stereo disc photographs and alternation flicker using a novel matching technology for detecting glaucoma progression

Nathan M. Radcliffe, Mitra Sehi, Ira B. Wallace, David S. Greenfield, Theodore Krupin, Robert Ritch

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

■ BACKGROUND AND OBJECTIVE: To compare agreement of automated alternation flicker and serial stereophotograph inspection for detection of progressive glaucoma. ■ PATIENTS AND METHODS: Serial photographs of patients with glaucoma with at least 36 months of follow-up and perimetry every 4 months were assessed by four graders using predefined criteria with both flicker and stereophotography. The main outcome measure was progressive neuroretinal rim deterioration as identified by each technique. ■ RESULTS: Forty eyes (20 patients) were included and 12 eyes progressed with perimetry. Using stereophotography, the overall agreement (kappa ± standard error) was 0.19 ± 0.06 for rim change, 0.78 ± 0.06 for disc hemorrhage, and -0.04 ± 0.06 for vessel movement. Using flicker, the overall agreement was similar for rim change (0.28 ± 0.06; P = .29), worse for disc hemorrhage (0.43 ± 0.06; P < .001), and better for vessel movement (0.22 ± 0.06; P = .002). The agreement between perimetric and disc progression was similar using stereophotography (0.10 ± 0.05) and flicker (0.19 ± 0.05; P = .20). ■ CONCLUSION: Agreement between flicker and stereophotography was similar.

Original languageEnglish (US)
Pages (from-to)629-634
Number of pages6
JournalOphthalmic Surgery Lasers and Imaging
Volume41
Issue number6
DOIs
StatePublished - Nov 1 2010

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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