Comparison of questionnaires used for screening and symptom identification in hypogonadal men

Aaron M. Bernie, Jason M. Scovell, Ranjith Ramasamy

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Late-onset hypogonadism (LOH) is typically defined as the cluster of symptoms appearing in aging men and accompanied by a decrease in serum testosterone levels. The identification of a simple screening tool with a high level of sensitivity and specificity to predict LOH has remained a challenge. To identify men with LOH, a variety of self-administered questionnaires have been developed including The Saint Louis University Androgen Deficiency in the Aging Male (ADAM) Questionnaire, The Quantitative ADAM (qADAM) Questionnaire, The Aging Male Symptoms (AMS) rating scale, The Massachusetts Male Aging Study (MMAS) questionnaire and The New England Research Institutes (NERI) hypogonadism questionnaire. The applicability of these questionnaires in the clinical setting is debated because some of the symptoms associated with LOH could be attributed to the natural process of aging and comorbidities. The goal of this review is to compare the utility and the validity of the different LOH questionnaires.

Original languageEnglish (US)
Pages (from-to)195-198
Number of pages4
JournalAging Male
Issue number4
StatePublished - Dec 1 2014
Externally publishedYes


  • Androgen deficiency
  • Androgen deficiency of the aging male
  • Hypogonadism questionnaires
  • Late-onset hypogonadism

ASJC Scopus subject areas

  • Geriatrics and Gerontology


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