Comparison of microscopic and endoscopic resection of third-ventricular colloid cysts: A systematic review and meta-analysis

Fatemeh Sayehmiri, Robert M. Starke, Daniel G. Eichberg, Milad Ghanikolahloo, Aryobarzan Rahmatian, Mobina Fathi, Kimia Vakili, Kaveh Ebrahimzadeh, Omidvar Rezaei, Mohammad Samadian, Seyed Ali Mousavinejad, Ehsan Nazari Maloumeh, Hesameddin Hoseini Tavasol, Guive Sharifi

Research output: Contribution to journalReview articlepeer-review

Abstract

Background and aim: Colloid cysts are uncommon benign lesions. There is a lack of consensus regarding the preferred surgical strategy for colloid cyst resection; the technique with the optimal rates of remission, recurrence, mortality, and complications is debatable. Materials and methods: To determine surgical outcomes, we performed a systematic review of the published literature on Colloid cysts. Eligible studies (n = 63) with a prospective or retrospective evaluation of endoscopic or microscopic resection of third ventricle colloid cysts were included, which contained data describing extents of resection, seizures, meningitis, and tumor recurrence. A total of 3143 patients (1741 microscopically and 1402 endoscopically operated) were included in the final analysis. Results: According to the results of the meta-analysis, there was a higher rate of gross total resection (GTR) (98.15% versus 91.29%, p = 0.00), need for shunting (4.75% versus 1.46%, p = 0.04), postoperative complications (20.68% versus 10.42%, P = 0.03), mean operating time (194.18 versus 113.04 min), and duration of hospitalization (7.85 versus 4.69 days) for microscopic resection compared with endoscopic resection. While endoscopic resection is associated with a higher rate of cyst recurrence (1.78% versus 0.00%, P = 0.00), there was no difference in reoperation rate (0.49% for endoscopic versus 0.09% for microscopic resection). Conclusion: Microsurgical resection of third ventricle colloid cysts was associated with a higher rate of GTR and a lower rate of recurrence, while there was a lower rate of postoperative complications, duration of surgery, and shorter hospitalization period in the endoscopic group.

Original languageEnglish (US)
Article number107179
JournalClinical Neurology and Neurosurgery
Volume215
DOIs
StatePublished - Apr 2022
Externally publishedYes

Keywords

  • Colloid cyst
  • Endoscopic surgery
  • Microscopic surgery
  • Third ventricle

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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