Comparison of mediational selected strategies and sequential designs for preventive trials: Comments on a proposal by pillow et al.

C. Hendricks Brown

Research output: Contribution to journalArticle

10 Scopus citations


Mediational selection designs can increase the chance of finding an intervention to be statistically better than a control when compared to interventions applied to a selected subpopulation such as all children of divorce. Selection based on poor mediational variable scores creates a high expectation that many subjects will benefit because it matches a population to a given intervention strategy. It does not permit examination of the impact on other subjects nor the possibility of interventions that may be tuned to the specific needs of different subpopulations. A sequence of trials each built on the results of previous ones has the potential for extending the results obtained from a mediational selection design.

Original languageEnglish (US)
Pages (from-to)837-846
Number of pages10
JournalAmerican Journal of Community Psychology
Issue number6
StatePublished - Dec 1 1991


ASJC Scopus subject areas

  • Health(social science)
  • Applied Psychology
  • Public Health, Environmental and Occupational Health

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