Comparison of in vitro potency of corticosteroids with ability to raise intraocular pressure

Herbert L. Cantrill, Paul F. Palmberg, Harry A. Zink, Stephen R. Waltman, Steven M. Podos, Bernard Becker

Research output: Contribution to journalArticle

69 Scopus citations

Abstract

Corticosteroid inhibition of lymphocyte transformation was compared with ability to raise intraocular pressure in ten corticosteroid-sensitive patients. Dexamethasone used topically in the same concentration as fluorometholone had more than three times the ocular hypertensive effect but was similar in in vitro potency. A dissociation was also found for prednisolone and medrysone.

Original languageEnglish (US)
Pages (from-to)1012-1017
Number of pages6
JournalAmerican journal of ophthalmology
Volume79
Issue number6
DOIs
StatePublished - Jun 1975
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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