Comparison of in vitro potency of corticosteroids with ability to raise intraocular pressure

Herbert L. Cantrill, Paul F. Palmberg, Harry A. Zink, Stephen R. Waltman, Steven M. Podos, Bernard Becker

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Abstract

Corticosteroid inhibition of lymphocyte transformation was compared with ability to raise intraocular pressure in ten corticosteroid-sensitive patients. Dexamethasone used topically in the same concentration as fluorometholone had more than three times the ocular hypertensive effect but was similar in in vitro potency. A dissociation was also found for prednisolone and medrysone.

Original languageEnglish (US)
Pages (from-to)1012-1017
Number of pages6
JournalAmerican journal of ophthalmology
Volume79
Issue number6
DOIs
StatePublished - Jun 1975

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ASJC Scopus subject areas

  • Ophthalmology

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