Comparison of in vitro potency of corticosteroids with ability to raise intraocular pressure

Herbert L. Cantrill; Paul F. Palmberg; Harry A. Zink; Stephen R. Waltman; Steven M. Podos; Bernard Becker

doi:10.1016/0002-9394(75)90687-X

Comparison of in vitro potency of corticosteroids with ability to raise intraocular pressure

Herbert L. Cantrill, Paul F. Palmberg, Harry A. Zink, Stephen R. Waltman, Steven M. Podos, Bernard Becker

Ophthalmology

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64 Scopus citations

Abstract

Corticosteroid inhibition of lymphocyte transformation was compared with ability to raise intraocular pressure in ten corticosteroid-sensitive patients. Dexamethasone used topically in the same concentration as fluorometholone had more than three times the ocular hypertensive effect but was similar in in vitro potency. A dissociation was also found for prednisolone and medrysone.

Original language	English (US)
Pages (from-to)	1012-1017
Number of pages	6
Journal	American journal of ophthalmology
Volume	79
Issue number	6
DOIs	https://doi.org/10.1016/0002-9394(75)90687-X
State	Published - Jun 1975

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ASJC Scopus subject areas

Ophthalmology

Cite this

Cantrill, H. L., Palmberg, P. F., Zink, H. A., Waltman, S. R., Podos, S. M., & Becker, B. (1975). Comparison of in vitro potency of corticosteroids with ability to raise intraocular pressure. American journal of ophthalmology, 79(6), 1012-1017. https://doi.org/10.1016/0002-9394(75)90687-X

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Access to Document

10.1016/0002-9394(75)90687-X