Abstract
Objective: To determine if outcomes after in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) using sperm from men with spinal cord injury (SCI group) differ from those of other etiologies of male factor infertility (non-SCI group). In men with SCI, to determine if IVF/ICSI outcomes differ with sperm obtained by penile vibratory stimulation (PVS group) versus electroejaculation (EEJ group). Design: Retrospective analysis. Setting: University medical center and major infertility center. Patient(s): Couples with male factor infertility due to SCI versus other etiologies. Intervention(s): PVS, EEJ, surgical sperm retrieval, and IVF/ICSI. Main Outcome Measure(s): Rates of fertilization, pregnancy, and live birth. Result(s): A total of 31 couples in the SCI group underwent 48 cycles of IVF/ICSI, and a total of 297 couples in the non-SCI group underwent 443 cycles of IVF/ICSI. The SCI group had lower fertilization rates but similar pregnancy and live birth rates compared with the non-SCI group. These rates, however, did not differ significantly when the PVS group was compared with the EEJ group. Conclusion(s): IVF/ICSI of sperm from men with SCI yield lower fertilization rates but similar pregnancy and live birth outcomes as IVF/ICSI of sperm from men with other etiologies of male factor infertility. Sperm collected by PVS versus EEJ in men with SCI appear to result in similar IVF/ICSI success rates.
| Original language | English |
|---|---|
| Pages (from-to) | 562-566 |
| Number of pages | 5 |
| Journal | Fertility and Sterility |
| Volume | 96 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 1 2011 |
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Keywords
- anejaculation
- electroejaculation
- intracytoplasmic sperm injection
- male infertility
- penile vibratory stimulation
- pregnancy outcomes
- semen
- sperm
- Spinal cord injuries
ASJC Scopus subject areas
- Obstetrics and Gynecology
- Reproductive Medicine
Cite this
Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries. / Kathiresan, Anupama S Q; Ibrahim, Emad; Aballa, Teodoro C.; Attia, George; Ory, Steven J.; Hoffman, David I.; Maxson, Wayne S.; Barrionuevo, Marcelo J.; Lynne, Charles M; Brackett, Nancy.
In: Fertility and Sterility, Vol. 96, No. 3, 01.09.2011, p. 562-566.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries
AU - Kathiresan, Anupama S Q
AU - Ibrahim, Emad
AU - Aballa, Teodoro C.
AU - Attia, George
AU - Ory, Steven J.
AU - Hoffman, David I.
AU - Maxson, Wayne S.
AU - Barrionuevo, Marcelo J.
AU - Lynne, Charles M
AU - Brackett, Nancy
PY - 2011/9/1
Y1 - 2011/9/1
N2 - Objective: To determine if outcomes after in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) using sperm from men with spinal cord injury (SCI group) differ from those of other etiologies of male factor infertility (non-SCI group). In men with SCI, to determine if IVF/ICSI outcomes differ with sperm obtained by penile vibratory stimulation (PVS group) versus electroejaculation (EEJ group). Design: Retrospective analysis. Setting: University medical center and major infertility center. Patient(s): Couples with male factor infertility due to SCI versus other etiologies. Intervention(s): PVS, EEJ, surgical sperm retrieval, and IVF/ICSI. Main Outcome Measure(s): Rates of fertilization, pregnancy, and live birth. Result(s): A total of 31 couples in the SCI group underwent 48 cycles of IVF/ICSI, and a total of 297 couples in the non-SCI group underwent 443 cycles of IVF/ICSI. The SCI group had lower fertilization rates but similar pregnancy and live birth rates compared with the non-SCI group. These rates, however, did not differ significantly when the PVS group was compared with the EEJ group. Conclusion(s): IVF/ICSI of sperm from men with SCI yield lower fertilization rates but similar pregnancy and live birth outcomes as IVF/ICSI of sperm from men with other etiologies of male factor infertility. Sperm collected by PVS versus EEJ in men with SCI appear to result in similar IVF/ICSI success rates.
AB - Objective: To determine if outcomes after in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) using sperm from men with spinal cord injury (SCI group) differ from those of other etiologies of male factor infertility (non-SCI group). In men with SCI, to determine if IVF/ICSI outcomes differ with sperm obtained by penile vibratory stimulation (PVS group) versus electroejaculation (EEJ group). Design: Retrospective analysis. Setting: University medical center and major infertility center. Patient(s): Couples with male factor infertility due to SCI versus other etiologies. Intervention(s): PVS, EEJ, surgical sperm retrieval, and IVF/ICSI. Main Outcome Measure(s): Rates of fertilization, pregnancy, and live birth. Result(s): A total of 31 couples in the SCI group underwent 48 cycles of IVF/ICSI, and a total of 297 couples in the non-SCI group underwent 443 cycles of IVF/ICSI. The SCI group had lower fertilization rates but similar pregnancy and live birth rates compared with the non-SCI group. These rates, however, did not differ significantly when the PVS group was compared with the EEJ group. Conclusion(s): IVF/ICSI of sperm from men with SCI yield lower fertilization rates but similar pregnancy and live birth outcomes as IVF/ICSI of sperm from men with other etiologies of male factor infertility. Sperm collected by PVS versus EEJ in men with SCI appear to result in similar IVF/ICSI success rates.
KW - anejaculation
KW - electroejaculation
KW - intracytoplasmic sperm injection
KW - male infertility
KW - penile vibratory stimulation
KW - pregnancy outcomes
KW - semen
KW - sperm
KW - Spinal cord injuries
UR - http://www.scopus.com/inward/record.url?scp=80052267546&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052267546&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2011.06.078
DO - 10.1016/j.fertnstert.2011.06.078
M3 - Article
C2 - 21807365
AN - SCOPUS:80052267546
VL - 96
SP - 562
EP - 566
JO - Fertility and Sterility
JF - Fertility and Sterility
SN - 0015-0282
IS - 3
ER -