Abstract
Objective: To determine if outcomes after in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) using sperm from men with spinal cord injury (SCI group) differ from those of other etiologies of male factor infertility (non-SCI group). In men with SCI, to determine if IVF/ICSI outcomes differ with sperm obtained by penile vibratory stimulation (PVS group) versus electroejaculation (EEJ group). Design: Retrospective analysis. Setting: University medical center and major infertility center. Patient(s): Couples with male factor infertility due to SCI versus other etiologies. Intervention(s): PVS, EEJ, surgical sperm retrieval, and IVF/ICSI. Main Outcome Measure(s): Rates of fertilization, pregnancy, and live birth. Result(s): A total of 31 couples in the SCI group underwent 48 cycles of IVF/ICSI, and a total of 297 couples in the non-SCI group underwent 443 cycles of IVF/ICSI. The SCI group had lower fertilization rates but similar pregnancy and live birth rates compared with the non-SCI group. These rates, however, did not differ significantly when the PVS group was compared with the EEJ group. Conclusion(s): IVF/ICSI of sperm from men with SCI yield lower fertilization rates but similar pregnancy and live birth outcomes as IVF/ICSI of sperm from men with other etiologies of male factor infertility. Sperm collected by PVS versus EEJ in men with SCI appear to result in similar IVF/ICSI success rates.
Original language | English (US) |
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Pages (from-to) | 562-566 |
Number of pages | 5 |
Journal | Fertility and sterility |
Volume | 96 |
Issue number | 3 |
DOIs | |
State | Published - Sep 2011 |
Keywords
- anejaculation
- electroejaculation
- intracytoplasmic sperm injection
- male infertility
- penile vibratory stimulation
- pregnancy outcomes
- semen
- sperm
- Spinal cord injuries
ASJC Scopus subject areas
- Obstetrics and Gynecology
- Reproductive Medicine