Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries

Anupama S Q Kathiresan, Emad Ibrahim, Teodoro C. Aballa, George Attia, Steven J. Ory, David I. Hoffman, Wayne S. Maxson, Marcelo J. Barrionuevo, Charles M Lynne, Nancy Brackett

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Objective: To determine if outcomes after in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) using sperm from men with spinal cord injury (SCI group) differ from those of other etiologies of male factor infertility (non-SCI group). In men with SCI, to determine if IVF/ICSI outcomes differ with sperm obtained by penile vibratory stimulation (PVS group) versus electroejaculation (EEJ group). Design: Retrospective analysis. Setting: University medical center and major infertility center. Patient(s): Couples with male factor infertility due to SCI versus other etiologies. Intervention(s): PVS, EEJ, surgical sperm retrieval, and IVF/ICSI. Main Outcome Measure(s): Rates of fertilization, pregnancy, and live birth. Result(s): A total of 31 couples in the SCI group underwent 48 cycles of IVF/ICSI, and a total of 297 couples in the non-SCI group underwent 443 cycles of IVF/ICSI. The SCI group had lower fertilization rates but similar pregnancy and live birth rates compared with the non-SCI group. These rates, however, did not differ significantly when the PVS group was compared with the EEJ group. Conclusion(s): IVF/ICSI of sperm from men with SCI yield lower fertilization rates but similar pregnancy and live birth outcomes as IVF/ICSI of sperm from men with other etiologies of male factor infertility. Sperm collected by PVS versus EEJ in men with SCI appear to result in similar IVF/ICSI success rates.

Original languageEnglish
Pages (from-to)562-566
Number of pages5
JournalFertility and Sterility
Volume96
Issue number3
DOIs
StatePublished - Sep 1 2011

Fingerprint

Intracytoplasmic Sperm Injections
Male Infertility
Fertilization in Vitro
Spinal Cord Injuries
Spermatozoa
Pregnancy Rate
Fertilization
Sperm Retrieval
Infertility
Outcome Assessment (Health Care)

Keywords

  • anejaculation
  • electroejaculation
  • intracytoplasmic sperm injection
  • male infertility
  • penile vibratory stimulation
  • pregnancy outcomes
  • semen
  • sperm
  • Spinal cord injuries

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries. / Kathiresan, Anupama S Q; Ibrahim, Emad; Aballa, Teodoro C.; Attia, George; Ory, Steven J.; Hoffman, David I.; Maxson, Wayne S.; Barrionuevo, Marcelo J.; Lynne, Charles M; Brackett, Nancy.

In: Fertility and Sterility, Vol. 96, No. 3, 01.09.2011, p. 562-566.

Research output: Contribution to journalArticle

Kathiresan, Anupama S Q ; Ibrahim, Emad ; Aballa, Teodoro C. ; Attia, George ; Ory, Steven J. ; Hoffman, David I. ; Maxson, Wayne S. ; Barrionuevo, Marcelo J. ; Lynne, Charles M ; Brackett, Nancy. / Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries. In: Fertility and Sterility. 2011 ; Vol. 96, No. 3. pp. 562-566.
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abstract = "Objective: To determine if outcomes after in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) using sperm from men with spinal cord injury (SCI group) differ from those of other etiologies of male factor infertility (non-SCI group). In men with SCI, to determine if IVF/ICSI outcomes differ with sperm obtained by penile vibratory stimulation (PVS group) versus electroejaculation (EEJ group). Design: Retrospective analysis. Setting: University medical center and major infertility center. Patient(s): Couples with male factor infertility due to SCI versus other etiologies. Intervention(s): PVS, EEJ, surgical sperm retrieval, and IVF/ICSI. Main Outcome Measure(s): Rates of fertilization, pregnancy, and live birth. Result(s): A total of 31 couples in the SCI group underwent 48 cycles of IVF/ICSI, and a total of 297 couples in the non-SCI group underwent 443 cycles of IVF/ICSI. The SCI group had lower fertilization rates but similar pregnancy and live birth rates compared with the non-SCI group. These rates, however, did not differ significantly when the PVS group was compared with the EEJ group. Conclusion(s): IVF/ICSI of sperm from men with SCI yield lower fertilization rates but similar pregnancy and live birth outcomes as IVF/ICSI of sperm from men with other etiologies of male factor infertility. Sperm collected by PVS versus EEJ in men with SCI appear to result in similar IVF/ICSI success rates.",
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T1 - Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries

AU - Kathiresan, Anupama S Q

AU - Ibrahim, Emad

AU - Aballa, Teodoro C.

AU - Attia, George

AU - Ory, Steven J.

AU - Hoffman, David I.

AU - Maxson, Wayne S.

AU - Barrionuevo, Marcelo J.

AU - Lynne, Charles M

AU - Brackett, Nancy

PY - 2011/9/1

Y1 - 2011/9/1

N2 - Objective: To determine if outcomes after in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) using sperm from men with spinal cord injury (SCI group) differ from those of other etiologies of male factor infertility (non-SCI group). In men with SCI, to determine if IVF/ICSI outcomes differ with sperm obtained by penile vibratory stimulation (PVS group) versus electroejaculation (EEJ group). Design: Retrospective analysis. Setting: University medical center and major infertility center. Patient(s): Couples with male factor infertility due to SCI versus other etiologies. Intervention(s): PVS, EEJ, surgical sperm retrieval, and IVF/ICSI. Main Outcome Measure(s): Rates of fertilization, pregnancy, and live birth. Result(s): A total of 31 couples in the SCI group underwent 48 cycles of IVF/ICSI, and a total of 297 couples in the non-SCI group underwent 443 cycles of IVF/ICSI. The SCI group had lower fertilization rates but similar pregnancy and live birth rates compared with the non-SCI group. These rates, however, did not differ significantly when the PVS group was compared with the EEJ group. Conclusion(s): IVF/ICSI of sperm from men with SCI yield lower fertilization rates but similar pregnancy and live birth outcomes as IVF/ICSI of sperm from men with other etiologies of male factor infertility. Sperm collected by PVS versus EEJ in men with SCI appear to result in similar IVF/ICSI success rates.

AB - Objective: To determine if outcomes after in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) using sperm from men with spinal cord injury (SCI group) differ from those of other etiologies of male factor infertility (non-SCI group). In men with SCI, to determine if IVF/ICSI outcomes differ with sperm obtained by penile vibratory stimulation (PVS group) versus electroejaculation (EEJ group). Design: Retrospective analysis. Setting: University medical center and major infertility center. Patient(s): Couples with male factor infertility due to SCI versus other etiologies. Intervention(s): PVS, EEJ, surgical sperm retrieval, and IVF/ICSI. Main Outcome Measure(s): Rates of fertilization, pregnancy, and live birth. Result(s): A total of 31 couples in the SCI group underwent 48 cycles of IVF/ICSI, and a total of 297 couples in the non-SCI group underwent 443 cycles of IVF/ICSI. The SCI group had lower fertilization rates but similar pregnancy and live birth rates compared with the non-SCI group. These rates, however, did not differ significantly when the PVS group was compared with the EEJ group. Conclusion(s): IVF/ICSI of sperm from men with SCI yield lower fertilization rates but similar pregnancy and live birth outcomes as IVF/ICSI of sperm from men with other etiologies of male factor infertility. Sperm collected by PVS versus EEJ in men with SCI appear to result in similar IVF/ICSI success rates.

KW - anejaculation

KW - electroejaculation

KW - intracytoplasmic sperm injection

KW - male infertility

KW - penile vibratory stimulation

KW - pregnancy outcomes

KW - semen

KW - sperm

KW - Spinal cord injuries

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