Comparison of in vitro corticosteroid response in pigmentary glaucoma and primary open-angle glaucoma

Harry A. Zink, Paul F. Palmberg, Alan Sugar, H. Saul Sugar, Herbert L. Cantrill, Bernard Becker, John F. Bigger

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

We used an in vitro assay utilizing corticosteroids to inhibit transformation of peripheral blood lymphocytes to evaluate a group of 20 patients with pigmentary glaucoma. The pigmentary glaucoma patient group did not manifest the markedly increased cellular sensitivity to corticosteroids associated with primary open-angle glaucoma. If increased sensitivity to corticosteroids plays an essential role in the pathogenesis of primary open-angle glaucoma, then pigmentary glaucoma appears to be etiologically, as well as clinically, a separate entity.

Original languageEnglish (US)
Pages (from-to)478-484
Number of pages7
JournalAmerican journal of ophthalmology
Volume80
Issue number3 PART 1
DOIs
StatePublished - Sep 1975
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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