Comparison of in vitro corticosteroid response in pigmentary glaucoma and primary open-angle glaucoma

Harry A. Zink, Paul Palmberg, Alan Sugar, H. Saul Sugar, Herbert L. Cantrill, Bernard Becker, John F. Bigger

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We used an in vitro assay utilizing corticosteroids to inhibit transformation of peripheral blood lymphocytes to evaluate a group of 20 patients with pigmentary glaucoma. The pigmentary glaucoma patient group did not manifest the markedly increased cellular sensitivity to corticosteroids associated with primary open-angle glaucoma. If increased sensitivity to corticosteroids plays an essential role in the pathogenesis of primary open-angle glaucoma, then pigmentary glaucoma appears to be etiologically, as well as clinically, a separate entity.

Original languageEnglish
Pages (from-to)478-484
Number of pages7
JournalAmerican Journal of Ophthalmology
Volume80
Issue number3 PART 1
StatePublished - Jan 1 1975
Externally publishedYes

Fingerprint

Open Angle Glaucoma
Adrenal Cortex Hormones
Lymphocytes
In Vitro Techniques
Primary Open Angle Glaucoma

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Zink, H. A., Palmberg, P., Sugar, A., Sugar, H. S., Cantrill, H. L., Becker, B., & Bigger, J. F. (1975). Comparison of in vitro corticosteroid response in pigmentary glaucoma and primary open-angle glaucoma. American Journal of Ophthalmology, 80(3 PART 1), 478-484.

Comparison of in vitro corticosteroid response in pigmentary glaucoma and primary open-angle glaucoma. / Zink, Harry A.; Palmberg, Paul; Sugar, Alan; Sugar, H. Saul; Cantrill, Herbert L.; Becker, Bernard; Bigger, John F.

In: American Journal of Ophthalmology, Vol. 80, No. 3 PART 1, 01.01.1975, p. 478-484.

Research output: Contribution to journalArticle

Zink, HA, Palmberg, P, Sugar, A, Sugar, HS, Cantrill, HL, Becker, B & Bigger, JF 1975, 'Comparison of in vitro corticosteroid response in pigmentary glaucoma and primary open-angle glaucoma', American Journal of Ophthalmology, vol. 80, no. 3 PART 1, pp. 478-484.
Zink, Harry A. ; Palmberg, Paul ; Sugar, Alan ; Sugar, H. Saul ; Cantrill, Herbert L. ; Becker, Bernard ; Bigger, John F. / Comparison of in vitro corticosteroid response in pigmentary glaucoma and primary open-angle glaucoma. In: American Journal of Ophthalmology. 1975 ; Vol. 80, No. 3 PART 1. pp. 478-484.
@article{85436e95511e4643a3da314b745e657b,
title = "Comparison of in vitro corticosteroid response in pigmentary glaucoma and primary open-angle glaucoma",
abstract = "We used an in vitro assay utilizing corticosteroids to inhibit transformation of peripheral blood lymphocytes to evaluate a group of 20 patients with pigmentary glaucoma. The pigmentary glaucoma patient group did not manifest the markedly increased cellular sensitivity to corticosteroids associated with primary open-angle glaucoma. If increased sensitivity to corticosteroids plays an essential role in the pathogenesis of primary open-angle glaucoma, then pigmentary glaucoma appears to be etiologically, as well as clinically, a separate entity.",
author = "Zink, {Harry A.} and Paul Palmberg and Alan Sugar and Sugar, {H. Saul} and Cantrill, {Herbert L.} and Bernard Becker and Bigger, {John F.}",
year = "1975",
month = "1",
day = "1",
language = "English",
volume = "80",
pages = "478--484",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "3 PART 1",

}

TY - JOUR

T1 - Comparison of in vitro corticosteroid response in pigmentary glaucoma and primary open-angle glaucoma

AU - Zink, Harry A.

AU - Palmberg, Paul

AU - Sugar, Alan

AU - Sugar, H. Saul

AU - Cantrill, Herbert L.

AU - Becker, Bernard

AU - Bigger, John F.

PY - 1975/1/1

Y1 - 1975/1/1

N2 - We used an in vitro assay utilizing corticosteroids to inhibit transformation of peripheral blood lymphocytes to evaluate a group of 20 patients with pigmentary glaucoma. The pigmentary glaucoma patient group did not manifest the markedly increased cellular sensitivity to corticosteroids associated with primary open-angle glaucoma. If increased sensitivity to corticosteroids plays an essential role in the pathogenesis of primary open-angle glaucoma, then pigmentary glaucoma appears to be etiologically, as well as clinically, a separate entity.

AB - We used an in vitro assay utilizing corticosteroids to inhibit transformation of peripheral blood lymphocytes to evaluate a group of 20 patients with pigmentary glaucoma. The pigmentary glaucoma patient group did not manifest the markedly increased cellular sensitivity to corticosteroids associated with primary open-angle glaucoma. If increased sensitivity to corticosteroids plays an essential role in the pathogenesis of primary open-angle glaucoma, then pigmentary glaucoma appears to be etiologically, as well as clinically, a separate entity.

UR - http://www.scopus.com/inward/record.url?scp=49549146971&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=49549146971&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:49549146971

VL - 80

SP - 478

EP - 484

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

SN - 0002-9394

IS - 3 PART 1

ER -