Comparison of fluid types for resuscitation after acute blood loss in mallard ducks (Anas platyrhynchos)

Marla Lichtenberger, Connie Orcutt, Carolyn Cray, Douglas H. Thamm, Daniel Debehnke, Cheryl Page, Lori Mull, Rebecca Kirby

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective The purpose of this study was to determine the LD50 for acute blood loss in mallard ducks (Anas platyrhynchos), compare the mortality rate among 3 fluid resuscitation groups, and determine the time required for a regenerative RBC response. Design Prospective study. Setting Medical College of Wisconsin Research facility. Animals Eighteen mallard ducks were included for the LD50 study and 28 for the fluid resuscitation study. Interventions Phlebotomy was performed during both the LD50 and fluid resuscitation studies. Ducks in the fluid resuscitation study received a 5 mL/kg intravenous bolus of crystalloids, hetastarch (HES), or a hemoglobin-based oxygen-carrying solution (HBOCS). Measurements and Main Results The LD50 for acute blood loss was 60% of total blood volume. This blood volume was removed in the fluid resuscitation study to create a model of acute blood loss. Following fluid administration, 6 birds in the crystalloid group (66%), 4 birds in the HES group (40%), and 2 birds in the HBOCS group (20%) died. No statistical difference in mortality rate was seen among the 3 fluid resuscitation groups. Relative polychromasia evaluated post-phlebotomy demonstrated regeneration starting at 24 hours and continuing through 48 hours. Conclusions The LD50 for acute blood loss in mallard ducks was 60% of their total blood volume. Although no statistical difference in mortality rate was appreciated among the 3 fluid resuscitation groups, a trend of decreased mortality rate was observed in the HBOCS group. An early regenerative response was apparent following acute blood loss.

Original languageEnglish
Pages (from-to)467-472
Number of pages6
JournalJournal of Veterinary Emergency and Critical Care
Volume19
Issue number5
DOIs
StatePublished - Oct 1 2009

Fingerprint

Ducks
Anas platyrhynchos
Resuscitation
ducks
Lethal Dose 50
lethal dose 50
blood
blood volume
Blood Volume
Hydroxyethyl Starch Derivatives
Birds
Hemoglobins
Phlebotomy
Mortality
hemoglobin
Oxygen
oxygen
birds
research facilities
fluids

Keywords

  • Colloids
  • Exotic pets (including birds)
  • Hemoglobin-based oxygen carrying solution
  • Regenerative anemia
  • Shock

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Comparison of fluid types for resuscitation after acute blood loss in mallard ducks (Anas platyrhynchos). / Lichtenberger, Marla; Orcutt, Connie; Cray, Carolyn; Thamm, Douglas H.; Debehnke, Daniel; Page, Cheryl; Mull, Lori; Kirby, Rebecca.

In: Journal of Veterinary Emergency and Critical Care, Vol. 19, No. 5, 01.10.2009, p. 467-472.

Research output: Contribution to journalArticle

Lichtenberger, Marla ; Orcutt, Connie ; Cray, Carolyn ; Thamm, Douglas H. ; Debehnke, Daniel ; Page, Cheryl ; Mull, Lori ; Kirby, Rebecca. / Comparison of fluid types for resuscitation after acute blood loss in mallard ducks (Anas platyrhynchos). In: Journal of Veterinary Emergency and Critical Care. 2009 ; Vol. 19, No. 5. pp. 467-472.
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