TY - JOUR
T1 - Comparison of early-onset neonatal sepsis caused by Escherichia coli and group B Streptococcus
AU - Mayor-Lynn, Kathleen
AU - González-Quintero, Víctor Hugo
AU - O'Sullivan, Mary Jo
AU - Hartstein, Alan I.
AU - Roger, Sonia
AU - Tamayo, Madeline
PY - 2005/5
Y1 - 2005/5
N2 - Objective: The purpose of this study was to compare maternal characteristics and neonatal morbidity and mortality rates that are associated with early-onset neonatal sepsis that is caused by group B Streptococcus and Escherichia coli. Study design: This was a retrospective review of newborn infants with a positive blood culture (and/or cerebrospinal fluid) that was positive for either E coli or group B Streptococcus during the first week of life. Data were abstracted from maternal and neonatal medical records. Results: Among 28,659 deliveries during the study period, 102 episodes of early-onset neonatal sepsis were identified, 61 of which were caused by group B Streptococcus and 41 of which were caused by E coli. E coli sepsis cases had a lower birth weight, a higher percentage with 5-minute Apgar score <7, and a longer stay in the hospital neonatal intensive care unit and required mechanical ventilation more frequently. Death after early-onset neonatal sepsis with E coli was also more frequent. Conclusion: Early-onset sepsis with E coli is associated with more morbidity and a higher mortality rate compared with early-onset group B Streptococcus.
AB - Objective: The purpose of this study was to compare maternal characteristics and neonatal morbidity and mortality rates that are associated with early-onset neonatal sepsis that is caused by group B Streptococcus and Escherichia coli. Study design: This was a retrospective review of newborn infants with a positive blood culture (and/or cerebrospinal fluid) that was positive for either E coli or group B Streptococcus during the first week of life. Data were abstracted from maternal and neonatal medical records. Results: Among 28,659 deliveries during the study period, 102 episodes of early-onset neonatal sepsis were identified, 61 of which were caused by group B Streptococcus and 41 of which were caused by E coli. E coli sepsis cases had a lower birth weight, a higher percentage with 5-minute Apgar score <7, and a longer stay in the hospital neonatal intensive care unit and required mechanical ventilation more frequently. Death after early-onset neonatal sepsis with E coli was also more frequent. Conclusion: Early-onset sepsis with E coli is associated with more morbidity and a higher mortality rate compared with early-onset group B Streptococcus.
KW - Early-onset neonatal sepsis
KW - Escherichia coli
KW - Group B streptococcus
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U2 - 10.1016/j.ajog.2004.12.031
DO - 10.1016/j.ajog.2004.12.031
M3 - Article
C2 - 15902130
AN - SCOPUS:20644448398
VL - 192
SP - 1437
EP - 1439
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
SN - 0002-9378
IS - 5 SPEC. ISS.
ER -