Anesthetic doses of morphine (1-4 mg/kg) were compared with 0.1-1.5% halothane plus 30% nitrous oxide to determine their effects on blood requirements and urinary output in 61 patients during and after open heart operations. Patients receiving morphine needed significantly more blood during bypass, during the entire operative procedure, and for the first 24 hr postoperatively than did patients anesthetized with halothane nitrous oxide. Urinary outputs were similar with both anesthetic techniques during all of these periods. The data suggest that morphine may increase total vascular capacitance more than halothane nitrous oxide does.
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine