Comparing retinal thickness measurements from cirrus spectral domain- and stratus time domain-optical coherence tomography

Wolfgang Geitzenauer, Christopher G. Kiss, Mary K. Durbin, Maria Teresa A Abunto, Thomas M. Callan, Paul F. Stetson, Mark R. Wieland, Neil M. Bressler, Giovanni Gregori, Ursula M. Schmidt-Erfurth

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Purpose: The purpose of this study was to compare retinal measurements obtained using spectral domain-optical coherence tomography with measurements obtained using time domain-optical coherence tomography. Methods: Three hundred and seventy subjects were recruited at three university-based and one community-based retina practice for a cross-sectional observational study. For each subject, one eye was enrolled as the study eye. A Stratus Fast Macular scan was performed, and a Cirrus 200 × 200 Macular Cube scan was performed. Both instruments segment the acquired images to generate retinal thickness values and report averages measured in nine subfields defined by the Early Treatment Diabetic Retinopathy Study. These average values were compared with each other quantitatively using linear regression and Bland-Altman plots. Results: Of the recruited subjects, 283 had acceptable images taken on the same day with both the Cirrus and Stratus devices. Mean differences between the instruments were noted in all subfields for all disease categories and ranged from 29 μm (outer superior subfield) to 54 μm (central subfield). Conclusion: Differences between time domain and spectral domain measurements of retinal thickness depend on pathology and location. Comparisons across instruments should be made with caution.

Original languageEnglish
Pages (from-to)596-606
Number of pages11
JournalRetina
Volume30
Issue number4
DOIs
StatePublished - Apr 1 2010

Fingerprint

Optical Coherence Tomography
Diabetic Retinopathy
Observational Studies
Retina
Linear Models
Cross-Sectional Studies
Pathology
Equipment and Supplies

Keywords

  • Age-related macular degeneration
  • Central retinal thickness
  • Diabetic retinopathy
  • Macular edema
  • Optical coherence tomography
  • Retinal thickness
  • Vitreomacular traction

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Geitzenauer, W., Kiss, C. G., Durbin, M. K., Abunto, M. T. A., Callan, T. M., Stetson, P. F., ... Schmidt-Erfurth, U. M. (2010). Comparing retinal thickness measurements from cirrus spectral domain- and stratus time domain-optical coherence tomography. Retina, 30(4), 596-606. https://doi.org/10.1097/IAE.0b013e3181c10711

Comparing retinal thickness measurements from cirrus spectral domain- and stratus time domain-optical coherence tomography. / Geitzenauer, Wolfgang; Kiss, Christopher G.; Durbin, Mary K.; Abunto, Maria Teresa A; Callan, Thomas M.; Stetson, Paul F.; Wieland, Mark R.; Bressler, Neil M.; Gregori, Giovanni; Schmidt-Erfurth, Ursula M.

In: Retina, Vol. 30, No. 4, 01.04.2010, p. 596-606.

Research output: Contribution to journalArticle

Geitzenauer, W, Kiss, CG, Durbin, MK, Abunto, MTA, Callan, TM, Stetson, PF, Wieland, MR, Bressler, NM, Gregori, G & Schmidt-Erfurth, UM 2010, 'Comparing retinal thickness measurements from cirrus spectral domain- and stratus time domain-optical coherence tomography', Retina, vol. 30, no. 4, pp. 596-606. https://doi.org/10.1097/IAE.0b013e3181c10711
Geitzenauer, Wolfgang ; Kiss, Christopher G. ; Durbin, Mary K. ; Abunto, Maria Teresa A ; Callan, Thomas M. ; Stetson, Paul F. ; Wieland, Mark R. ; Bressler, Neil M. ; Gregori, Giovanni ; Schmidt-Erfurth, Ursula M. / Comparing retinal thickness measurements from cirrus spectral domain- and stratus time domain-optical coherence tomography. In: Retina. 2010 ; Vol. 30, No. 4. pp. 596-606.
@article{cec1738ffa974cc3b6111bd59aa09170,
title = "Comparing retinal thickness measurements from cirrus spectral domain- and stratus time domain-optical coherence tomography",
abstract = "Purpose: The purpose of this study was to compare retinal measurements obtained using spectral domain-optical coherence tomography with measurements obtained using time domain-optical coherence tomography. Methods: Three hundred and seventy subjects were recruited at three university-based and one community-based retina practice for a cross-sectional observational study. For each subject, one eye was enrolled as the study eye. A Stratus Fast Macular scan was performed, and a Cirrus 200 × 200 Macular Cube scan was performed. Both instruments segment the acquired images to generate retinal thickness values and report averages measured in nine subfields defined by the Early Treatment Diabetic Retinopathy Study. These average values were compared with each other quantitatively using linear regression and Bland-Altman plots. Results: Of the recruited subjects, 283 had acceptable images taken on the same day with both the Cirrus and Stratus devices. Mean differences between the instruments were noted in all subfields for all disease categories and ranged from 29 μm (outer superior subfield) to 54 μm (central subfield). Conclusion: Differences between time domain and spectral domain measurements of retinal thickness depend on pathology and location. Comparisons across instruments should be made with caution.",
keywords = "Age-related macular degeneration, Central retinal thickness, Diabetic retinopathy, Macular edema, Optical coherence tomography, Retinal thickness, Vitreomacular traction",
author = "Wolfgang Geitzenauer and Kiss, {Christopher G.} and Durbin, {Mary K.} and Abunto, {Maria Teresa A} and Callan, {Thomas M.} and Stetson, {Paul F.} and Wieland, {Mark R.} and Bressler, {Neil M.} and Giovanni Gregori and Schmidt-Erfurth, {Ursula M.}",
year = "2010",
month = "4",
day = "1",
doi = "10.1097/IAE.0b013e3181c10711",
language = "English",
volume = "30",
pages = "596--606",
journal = "Retina",
issn = "0275-004X",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Comparing retinal thickness measurements from cirrus spectral domain- and stratus time domain-optical coherence tomography

AU - Geitzenauer, Wolfgang

AU - Kiss, Christopher G.

AU - Durbin, Mary K.

AU - Abunto, Maria Teresa A

AU - Callan, Thomas M.

AU - Stetson, Paul F.

AU - Wieland, Mark R.

AU - Bressler, Neil M.

AU - Gregori, Giovanni

AU - Schmidt-Erfurth, Ursula M.

PY - 2010/4/1

Y1 - 2010/4/1

N2 - Purpose: The purpose of this study was to compare retinal measurements obtained using spectral domain-optical coherence tomography with measurements obtained using time domain-optical coherence tomography. Methods: Three hundred and seventy subjects were recruited at three university-based and one community-based retina practice for a cross-sectional observational study. For each subject, one eye was enrolled as the study eye. A Stratus Fast Macular scan was performed, and a Cirrus 200 × 200 Macular Cube scan was performed. Both instruments segment the acquired images to generate retinal thickness values and report averages measured in nine subfields defined by the Early Treatment Diabetic Retinopathy Study. These average values were compared with each other quantitatively using linear regression and Bland-Altman plots. Results: Of the recruited subjects, 283 had acceptable images taken on the same day with both the Cirrus and Stratus devices. Mean differences between the instruments were noted in all subfields for all disease categories and ranged from 29 μm (outer superior subfield) to 54 μm (central subfield). Conclusion: Differences between time domain and spectral domain measurements of retinal thickness depend on pathology and location. Comparisons across instruments should be made with caution.

AB - Purpose: The purpose of this study was to compare retinal measurements obtained using spectral domain-optical coherence tomography with measurements obtained using time domain-optical coherence tomography. Methods: Three hundred and seventy subjects were recruited at three university-based and one community-based retina practice for a cross-sectional observational study. For each subject, one eye was enrolled as the study eye. A Stratus Fast Macular scan was performed, and a Cirrus 200 × 200 Macular Cube scan was performed. Both instruments segment the acquired images to generate retinal thickness values and report averages measured in nine subfields defined by the Early Treatment Diabetic Retinopathy Study. These average values were compared with each other quantitatively using linear regression and Bland-Altman plots. Results: Of the recruited subjects, 283 had acceptable images taken on the same day with both the Cirrus and Stratus devices. Mean differences between the instruments were noted in all subfields for all disease categories and ranged from 29 μm (outer superior subfield) to 54 μm (central subfield). Conclusion: Differences between time domain and spectral domain measurements of retinal thickness depend on pathology and location. Comparisons across instruments should be made with caution.

KW - Age-related macular degeneration

KW - Central retinal thickness

KW - Diabetic retinopathy

KW - Macular edema

KW - Optical coherence tomography

KW - Retinal thickness

KW - Vitreomacular traction

UR - http://www.scopus.com/inward/record.url?scp=77951157629&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951157629&partnerID=8YFLogxK

U2 - 10.1097/IAE.0b013e3181c10711

DO - 10.1097/IAE.0b013e3181c10711

M3 - Article

C2 - 20098347

AN - SCOPUS:77951157629

VL - 30

SP - 596

EP - 606

JO - Retina

JF - Retina

SN - 0275-004X

IS - 4

ER -