Comparative evaluation of Kodak EDR2 and XV2 films for verification of intensity modulated radiation therapy

Nesrin Dogan, Leonid B. Leybovich, Anil Sethi

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Film dosimetry provides a convenient tool to determine dose distributions, especially for verification of IMRT plans. However, the film response to radiation shows a significant dependence on depth, energy and field size that compromise the accuracy of measurements. Kodak's XV2 film has a low saturation dose (∼ 100 cGy) and, consequently, a relatively short region of linear dose-response. The recently introduced Kodak extended range EDR2 film was reported to have a linear dose-response region extending to 500 cGy. this increased dose range may be prticularly useful in the verification of IMRT plans. In this work, the dependence of Kodak EDR2 film's response on the depth, field size and energy was evaluated and compared with Kodak XV2 film. Co-60, 6 MV, 10 MV and 18 MV beams were used. Field sized were 2 x 2, 6 x 6, 10 x 10, 14 x 14, 18 x 18 and 24 x 24 cm 2. Doses for XV2 and EDR2 films were 80 cGy and 300 cGy, respectively. Optical density was converted to dose using depth-corrected sensitometric (Hurter and Driffield, or H&D) curves. For each field size, XV2 and EDR2 depth-dose curves were compared with ion chamber depth-dose curves. Both films demonstrated similar (within 1%) field size dependence. The deviation from the ion chamber for both films was small for the fields ranging from 2 x 2 to 10 x 10 cm 2: ≤2% for 6, 10 and 18 MV beams. No deviation was observed for the Co-60 beam. As the field size increased to 24 x 24 cm 2, the deviation became significant for both films: ∼7.5% for Co-60, ∼5% for 6 MV and 10 MV, and ∼6% for 18 MV. During the verification of IMRT plans, EDR2 film showed a better agreement with the calculated dose distributions that the XV2 film.

Original languageEnglish (US)
Pages (from-to)4121-4130
Number of pages10
JournalPhysics in Medicine and Biology
Volume47
Issue number22
DOIs
StatePublished - Nov 21 2002
Externally publishedYes

Fingerprint

Radiotherapy
radiation therapy
Film Dosimetry
Ions
evaluation
dosage
Radiation
Dosimetry
Ionization chambers
ionization chambers
deviation
curves
Density (optical)
optical density
dosimeters
saturation

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging
  • Physics and Astronomy (miscellaneous)
  • Radiological and Ultrasound Technology

Cite this

Comparative evaluation of Kodak EDR2 and XV2 films for verification of intensity modulated radiation therapy. / Dogan, Nesrin; Leybovich, Leonid B.; Sethi, Anil.

In: Physics in Medicine and Biology, Vol. 47, No. 22, 21.11.2002, p. 4121-4130.

Research output: Contribution to journalArticle

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abstract = "Film dosimetry provides a convenient tool to determine dose distributions, especially for verification of IMRT plans. However, the film response to radiation shows a significant dependence on depth, energy and field size that compromise the accuracy of measurements. Kodak's XV2 film has a low saturation dose (∼ 100 cGy) and, consequently, a relatively short region of linear dose-response. The recently introduced Kodak extended range EDR2 film was reported to have a linear dose-response region extending to 500 cGy. this increased dose range may be prticularly useful in the verification of IMRT plans. In this work, the dependence of Kodak EDR2 film's response on the depth, field size and energy was evaluated and compared with Kodak XV2 film. Co-60, 6 MV, 10 MV and 18 MV beams were used. Field sized were 2 x 2, 6 x 6, 10 x 10, 14 x 14, 18 x 18 and 24 x 24 cm 2. Doses for XV2 and EDR2 films were 80 cGy and 300 cGy, respectively. Optical density was converted to dose using depth-corrected sensitometric (Hurter and Driffield, or H&D) curves. For each field size, XV2 and EDR2 depth-dose curves were compared with ion chamber depth-dose curves. Both films demonstrated similar (within 1{\%}) field size dependence. The deviation from the ion chamber for both films was small for the fields ranging from 2 x 2 to 10 x 10 cm 2: ≤2{\%} for 6, 10 and 18 MV beams. No deviation was observed for the Co-60 beam. As the field size increased to 24 x 24 cm 2, the deviation became significant for both films: ∼7.5{\%} for Co-60, ∼5{\%} for 6 MV and 10 MV, and ∼6{\%} for 18 MV. During the verification of IMRT plans, EDR2 film showed a better agreement with the calculated dose distributions that the XV2 film.",
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