Comparative efficacy of the SLT versus LASAG Nd:YAG delivery systems in rabbits

Kimberly L. Guo, Carol L. Karp, Eve J. Higginbotham, Eric O. Griffin, Marilyn C. Kincaid

Research output: Contribution to journalArticlepeer-review


Purpose: The efficacy of two types of contact transscleral Nd:YAG laser delivery systems, a synthetic sapphire-tipped laser probe connected to a Surgical Laser Technologies (SLT) laser and a quartz fiberoptic tip connected to a LASAG Microrupter III, was compared. Method: A total of nine pigmented rabbits underwent transscleral LASAG cycloablation in one eye (3.2 W, 0.5 s); an additional eight rabbits underwent Surgical Laser Technologies cycloablation (3.0 W, 0.5 s). Results: The maximum difference in intraocular pressure between the experimental versus fellow eyes was - 15.09 mm Hg (±0.25) with the LASAG and -13.16 mm Hg (±3.12) with the SLT laser; in both delivery systems, this difference was achieved 4 days postoperatively. The differences between the two groups in duration of pressure reduction was not statistically significant (p = 0.83). Conclusion: These data suggest that these delivery systems are equally effective in lowering intraocular pressure in rabbits. Histological changes of the ciliary processes and adjacent ocular tissue are presented.

Original languageEnglish (US)
Pages (from-to)268-273
Number of pages6
JournalJournal of glaucoma
Issue number4
StatePublished - Aug 1995


  • Ciliary body
  • Ciliary processes
  • Cycloablation
  • Glaucoma
  • Intraocular pressure
  • Laser

ASJC Scopus subject areas

  • Ophthalmology


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