Abstract
The effects of comorbid depression and anxiety were compared to the effects of depression alone and anxiety alone on pregnancy mood states and biochemistry and on neonatal outcomes in a large multi-ethnic sample. At the prenatal period the comorbid and depressed groups had higher scores than the other groups on the depression measure. But, the comorbid group had higher anxiety, anger and daily hassles scores than the other groups, and they had lower dopamine levels. As compared to the non-depressed group, they also reported more sleep disturbances and relationship problems. The comorbid group also experienced a greater incidence of prematurity than the depressed, the high anxiety and the non-depressed groups. Although the comorbid and anxiety groups were lower birthweight than the non-depressed and depressed groups, the comorbid group did not differ from the depressed and anxiety groups on birth length. The neonates of the comorbid and depressed groups had higher cortisol and norepinephrine and lower dopamine and serotonin levels than the neonates of the anxiety and non-depressed groups as well as greater relative right frontal EEG. These data suggest that for some measures comorbidity of depression and anxiety is the worst condition (e.g., incidence of prematurity), while for others, comorbidity is no more impactful than depression alone.
| Original language | English |
|---|---|
| Pages (from-to) | 23-29 |
| Number of pages | 7 |
| Journal | Infant Behavior and Development |
| Volume | 33 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 1 2010 |
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Keywords
- Anxiety
- Comorbid depression
- Neonatal outcome
- Pregnancy
ASJC Scopus subject areas
- Developmental and Educational Psychology
Cite this
Comorbid depression and anxiety effects on pregnancy and neonatal outcome. / Field, Tiffany M; Diego, Miguel A; Hernandez-Reif, Maria; Figueiredo, Barbara; Deeds, Osvelia; Ascencio, Angela; Schanberg, Saul; Kuhn, Cynthia.
In: Infant Behavior and Development, Vol. 33, No. 1, 01.02.2010, p. 23-29.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comorbid depression and anxiety effects on pregnancy and neonatal outcome
AU - Field, Tiffany M
AU - Diego, Miguel A
AU - Hernandez-Reif, Maria
AU - Figueiredo, Barbara
AU - Deeds, Osvelia
AU - Ascencio, Angela
AU - Schanberg, Saul
AU - Kuhn, Cynthia
PY - 2010/2/1
Y1 - 2010/2/1
N2 - The effects of comorbid depression and anxiety were compared to the effects of depression alone and anxiety alone on pregnancy mood states and biochemistry and on neonatal outcomes in a large multi-ethnic sample. At the prenatal period the comorbid and depressed groups had higher scores than the other groups on the depression measure. But, the comorbid group had higher anxiety, anger and daily hassles scores than the other groups, and they had lower dopamine levels. As compared to the non-depressed group, they also reported more sleep disturbances and relationship problems. The comorbid group also experienced a greater incidence of prematurity than the depressed, the high anxiety and the non-depressed groups. Although the comorbid and anxiety groups were lower birthweight than the non-depressed and depressed groups, the comorbid group did not differ from the depressed and anxiety groups on birth length. The neonates of the comorbid and depressed groups had higher cortisol and norepinephrine and lower dopamine and serotonin levels than the neonates of the anxiety and non-depressed groups as well as greater relative right frontal EEG. These data suggest that for some measures comorbidity of depression and anxiety is the worst condition (e.g., incidence of prematurity), while for others, comorbidity is no more impactful than depression alone.
AB - The effects of comorbid depression and anxiety were compared to the effects of depression alone and anxiety alone on pregnancy mood states and biochemistry and on neonatal outcomes in a large multi-ethnic sample. At the prenatal period the comorbid and depressed groups had higher scores than the other groups on the depression measure. But, the comorbid group had higher anxiety, anger and daily hassles scores than the other groups, and they had lower dopamine levels. As compared to the non-depressed group, they also reported more sleep disturbances and relationship problems. The comorbid group also experienced a greater incidence of prematurity than the depressed, the high anxiety and the non-depressed groups. Although the comorbid and anxiety groups were lower birthweight than the non-depressed and depressed groups, the comorbid group did not differ from the depressed and anxiety groups on birth length. The neonates of the comorbid and depressed groups had higher cortisol and norepinephrine and lower dopamine and serotonin levels than the neonates of the anxiety and non-depressed groups as well as greater relative right frontal EEG. These data suggest that for some measures comorbidity of depression and anxiety is the worst condition (e.g., incidence of prematurity), while for others, comorbidity is no more impactful than depression alone.
KW - Anxiety
KW - Comorbid depression
KW - Neonatal outcome
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=75549084807&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=75549084807&partnerID=8YFLogxK
U2 - 10.1016/j.infbeh.2009.10.004
DO - 10.1016/j.infbeh.2009.10.004
M3 - Article
C2 - 19945170
AN - SCOPUS:75549084807
VL - 33
SP - 23
EP - 29
JO - Infant Behavior and Development
JF - Infant Behavior and Development
SN - 0163-6383
IS - 1
ER -