Comment to the paper: Palliative functional hemispherectomy for treatment of refractory status epilepticus associated with Alpers' disease

Michael Duchowny

doi:10.1007/s00381-011-1501-2

Comment to the paper: Palliative functional hemispherectomy for treatment of refractory status epilepticus associated with Alpers' disease

Michael Duchowny

Neurology

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Introduction: Performing epilepsy surgery in a child with a neurodegenerative illness is a relatively unexplored challenge. In this issue of CNS, Lupashko and coauthors report the use of epilepsy surgery to eliminate seizures without influencing the underlying progressive disorder. Method: Functional hemispherectomy was performed in a 4-year-old girl with seizures caused by Alpers' disease. Results: Seizure freedom and an improved quality of life were achieved briefly despite deteriorating neurologic status. Conclusion: Further studies will be needed to confirm the positive benefits of palliative epilepsy surgery in children with progressive neurologic illnesses.

Original language	English (US)
Pages (from-to)	1327-1328
Number of pages	2
Journal	Child's Nervous System
Volume	27
Issue number	8
DOIs	https://doi.org/10.1007/s00381-011-1501-2
State	Published - Aug 1 2011

Keywords

Epilepsy surgery
Hemispherectomy
Palliation

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Clinical Neurology

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title = "Comment to the paper: Palliative functional hemispherectomy for treatment of refractory status epilepticus associated with Alpers' disease",

abstract = "Introduction: Performing epilepsy surgery in a child with a neurodegenerative illness is a relatively unexplored challenge. In this issue of CNS, Lupashko and coauthors report the use of epilepsy surgery to eliminate seizures without influencing the underlying progressive disorder. Method: Functional hemispherectomy was performed in a 4-year-old girl with seizures caused by Alpers' disease. Results: Seizure freedom and an improved quality of life were achieved briefly despite deteriorating neurologic status. Conclusion: Further studies will be needed to confirm the positive benefits of palliative epilepsy surgery in children with progressive neurologic illnesses.",

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AB - Introduction: Performing epilepsy surgery in a child with a neurodegenerative illness is a relatively unexplored challenge. In this issue of CNS, Lupashko and coauthors report the use of epilepsy surgery to eliminate seizures without influencing the underlying progressive disorder. Method: Functional hemispherectomy was performed in a 4-year-old girl with seizures caused by Alpers' disease. Results: Seizure freedom and an improved quality of life were achieved briefly despite deteriorating neurologic status. Conclusion: Further studies will be needed to confirm the positive benefits of palliative epilepsy surgery in children with progressive neurologic illnesses.

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