Abstract
Amlodipine is a highly effective and safe antihypertensive dihydropyridine calcium channel blocker. It is even more effective when used in combination with other antihypertensive medications, including hydrochlorothiazide. When antihypertensive calcium channel blockers were first introduced, evidence in the laboratory that they had some natriuretic properties was adduced to suggest that they would be "the diuretics of the 1990s." This turned out not to be the case. Because of its clinical efficacy, amlodipine is frequently used in fixed-dose combination products, but it is not likely to replace hydrochlorothiazide.
| Original language | English |
|---|---|
| Pages (from-to) | 284-290 |
| Number of pages | 7 |
| Journal | Current Hypertension Reports |
| Volume | 9 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 1 2007 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Combination therapy with renin-angiotensin system blockers : Will amlodipine replace hydrochlorothiazide? / Tejada, Thor; Fornoni, Alessia; Lenz, Oliver; Materson, Barry J.
In: Current Hypertension Reports, Vol. 9, No. 4, 01.08.2007, p. 284-290.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Combination therapy with renin-angiotensin system blockers
T2 - Will amlodipine replace hydrochlorothiazide?
AU - Tejada, Thor
AU - Fornoni, Alessia
AU - Lenz, Oliver
AU - Materson, Barry J
PY - 2007/8/1
Y1 - 2007/8/1
N2 - Amlodipine is a highly effective and safe antihypertensive dihydropyridine calcium channel blocker. It is even more effective when used in combination with other antihypertensive medications, including hydrochlorothiazide. When antihypertensive calcium channel blockers were first introduced, evidence in the laboratory that they had some natriuretic properties was adduced to suggest that they would be "the diuretics of the 1990s." This turned out not to be the case. Because of its clinical efficacy, amlodipine is frequently used in fixed-dose combination products, but it is not likely to replace hydrochlorothiazide.
AB - Amlodipine is a highly effective and safe antihypertensive dihydropyridine calcium channel blocker. It is even more effective when used in combination with other antihypertensive medications, including hydrochlorothiazide. When antihypertensive calcium channel blockers were first introduced, evidence in the laboratory that they had some natriuretic properties was adduced to suggest that they would be "the diuretics of the 1990s." This turned out not to be the case. Because of its clinical efficacy, amlodipine is frequently used in fixed-dose combination products, but it is not likely to replace hydrochlorothiazide.
UR - http://www.scopus.com/inward/record.url?scp=34548543777&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548543777&partnerID=8YFLogxK
U2 - 10.1007/s11906-007-0052-0
DO - 10.1007/s11906-007-0052-0
M3 - Article
VL - 9
SP - 284
EP - 290
JO - Current Hypertension Reports
JF - Current Hypertension Reports
SN - 1522-6417
IS - 4
ER -