Colorimetric detection of cyanide with a chromogenic oxazine

Massimiliano Tomasulo; Françisco M. Raymo

doi:10.1021/ol051750m

Colorimetric detection of cyanide with a chromogenic oxazine

Massimiliano Tomasulo, Françisco M. Raymo

Chemistry

Research output: Contribution to journal › Article › peer-review

222 Scopus citations

Abstract

(Chemical Equation Presented) We have designed a chromogenic oxazine for the colorimetric detection of cyanide. Indeed, the [1,3]oxazine ring of our compound opens to form a 4-nitrophenylazophenolate chromophore in response to cyanide. This quantitative chromogenic transformation permits the detection of micromolar concentrations of cyanide in water. Furthermore, our chromogenic oxazine is insensitive to the presence of large concentrations of fluoride, chloride, bromide, or iodide anions, which are generally the principal interferents in the colorimetric detection of cyanide.

Original language	English (US)
Pages (from-to)	4633-4636
Number of pages	4
Journal	Organic letters
Volume	7
Issue number	21
DOIs	https://doi.org/10.1021/ol051750m
State	Published - Oct 13 2005

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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abstract = "(Chemical Equation Presented) We have designed a chromogenic oxazine for the colorimetric detection of cyanide. Indeed, the [1,3]oxazine ring of our compound opens to form a 4-nitrophenylazophenolate chromophore in response to cyanide. This quantitative chromogenic transformation permits the detection of micromolar concentrations of cyanide in water. Furthermore, our chromogenic oxazine is insensitive to the presence of large concentrations of fluoride, chloride, bromide, or iodide anions, which are generally the principal interferents in the colorimetric detection of cyanide.",

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N2 - (Chemical Equation Presented) We have designed a chromogenic oxazine for the colorimetric detection of cyanide. Indeed, the [1,3]oxazine ring of our compound opens to form a 4-nitrophenylazophenolate chromophore in response to cyanide. This quantitative chromogenic transformation permits the detection of micromolar concentrations of cyanide in water. Furthermore, our chromogenic oxazine is insensitive to the presence of large concentrations of fluoride, chloride, bromide, or iodide anions, which are generally the principal interferents in the colorimetric detection of cyanide.

AB - (Chemical Equation Presented) We have designed a chromogenic oxazine for the colorimetric detection of cyanide. Indeed, the [1,3]oxazine ring of our compound opens to form a 4-nitrophenylazophenolate chromophore in response to cyanide. This quantitative chromogenic transformation permits the detection of micromolar concentrations of cyanide in water. Furthermore, our chromogenic oxazine is insensitive to the presence of large concentrations of fluoride, chloride, bromide, or iodide anions, which are generally the principal interferents in the colorimetric detection of cyanide.

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