Colorectal liver metastasis

Overview of treatment paradigm highlighting the role of ablation

Shree Venkat, Prasoon P. Mohan, Ripal T. Gandhi

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

OBJECTIVE. The objective of this article is to discuss the current treatment options for colorectal cancer (CRC) liver metastases and the role of ablation. CONCLUSION. A randomized control trial of ablation combined with chemotherapy showed improved overall survival compared with chemotherapy alone. Local recurrence rates are comparable to those associated with resection when ablative margins of more than 5 mm are achieved and target lesions are smaller than 3 cm. In patients with unresectable disease, ablation for curative intent should be considered.

Original languageEnglish (US)
Pages (from-to)883-890
Number of pages8
JournalAmerican Journal of Roentgenology
Volume210
Issue number4
DOIs
StatePublished - Apr 1 2018

Fingerprint

Neoplasm Metastasis
Drug Therapy
Liver
Liver Neoplasms
Colorectal Neoplasms
Recurrence
Survival
Therapeutics

Keywords

  • Colorectal cancer
  • Liver metastases
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Colorectal liver metastasis : Overview of treatment paradigm highlighting the role of ablation. / Venkat, Shree; Mohan, Prasoon P.; Gandhi, Ripal T.

In: American Journal of Roentgenology, Vol. 210, No. 4, 01.04.2018, p. 883-890.

Research output: Contribution to journalReview article

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AB - OBJECTIVE. The objective of this article is to discuss the current treatment options for colorectal cancer (CRC) liver metastases and the role of ablation. CONCLUSION. A randomized control trial of ablation combined with chemotherapy showed improved overall survival compared with chemotherapy alone. Local recurrence rates are comparable to those associated with resection when ablative margins of more than 5 mm are achieved and target lesions are smaller than 3 cm. In patients with unresectable disease, ablation for curative intent should be considered.

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