Color duplex sonography in severe transplant renal artery stenosis: a comparison of end-to-end and end-to-side arterial anastomoses

Jing Gao, Jian Chu Li, Meng Su Xiao, Amelia Ng, David Trost, Michael Goldstein, Sandip Kapur, John Wang, David Serur, Qing Dai, Yu Xin Jiang, Robert J. Min

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Objective: The aim of this study was to investigate differences in Doppler parameters between severe transplant renal artery stenosis (TRAS, arterial lumen reduction >80%) with end-to-end (EE) arterial anastomosis and that with end-to-side (ES) arterial anastomosis. Methods: We retrospectively reviewed color duplex sonography (CDUS) and digital subtraction angiography (DSA) images in 38 patients with severe TRAS (19 cases with EE and 19 cases with ES) between January 1, 2000, and December 31, 2006. Doppler parameters were analyzed, including peak systolic velocity (PSV) in the iliac artery, PSV at the arterial anastomosis, PSV in the transplant renal artery, PSV ratio of the stenotic artery/artery proximal to the stenosis, and acceleration time (AT) in the artery distal to the stenosis (in the intrarenal artery). All 38 cases with severe TRAS were initially diagnosed with CDUS and confirmed by DSA. Results: There were significant differences in PSV in the stenotic artery (P<.01), PSV in the iliac artery (P<.001), and PSV ratios of stenotic artery/artery proximal to the stenosis (P<.001) between arterial anastomosis of EE and that of ES. There was no statistically significant difference in AT in the intrarenal artery between the two types of anastomosis (P>.05). Conclusion: Significantly different PSVs in the stenotic artery, the iliac artery, and the PSV ratio between EE and ES arterial anastomoses should be considered in the interpretation of CDUS when screening for severe TRAS. Different criteria of CDUS need to be established depending on the type of arterial anastomosis in order to improve the accuracy in diagnosing severe TRAS.

Original languageEnglish (US)
Pages (from-to)116-122
Number of pages7
JournalClinical Imaging
Issue number2
StatePublished - Mar 2009


  • Color Doppler
  • Color duplex sonography
  • Renal transplant
  • Transplant renal artery stenosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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