TY - JOUR
T1 - Color Doppler demonstration of segmental portal flow reversal
T2 - An early sign of hepatic veno-occlusive disease in an infant
AU - Ghersin, Eduard
AU - Brook, Olga R.
AU - Gaitini, Diana
AU - Engel, Ahuva
PY - 2003/10/1
Y1 - 2003/10/1
N2 - Hepatic veno-occlusive disease (HVOD) is a relatively frequent complication of bone marrow transplantation (BMT), with a reported prevalence of 1% to 54%. The role of color duplex ultrasonography (CDU) in the diagnosis and monitoring of HVOD is controversial; some authors advocate its use, whereas others find it insensitive and nonspecific. Hepatofugal flow in the main portal vein is regarded as a relatively specific finding of severe HVOD; however, it is of limited value because it seldom occurs. Here we report HVOD in an infant who previously underwent BMT. The HVOD was diagnosed early by demonstration of hepatofugal flow in only 1 segmental portal vein. After treatment with high-dose methylprednisolone and defibrotide, CDU showed reversal to hepatopetal flow accompanied by marked clinical improvement.
AB - Hepatic veno-occlusive disease (HVOD) is a relatively frequent complication of bone marrow transplantation (BMT), with a reported prevalence of 1% to 54%. The role of color duplex ultrasonography (CDU) in the diagnosis and monitoring of HVOD is controversial; some authors advocate its use, whereas others find it insensitive and nonspecific. Hepatofugal flow in the main portal vein is regarded as a relatively specific finding of severe HVOD; however, it is of limited value because it seldom occurs. Here we report HVOD in an infant who previously underwent BMT. The HVOD was diagnosed early by demonstration of hepatofugal flow in only 1 segmental portal vein. After treatment with high-dose methylprednisolone and defibrotide, CDU showed reversal to hepatopetal flow accompanied by marked clinical improvement.
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U2 - 10.7863/jum.2003.22.10.1103
DO - 10.7863/jum.2003.22.10.1103
M3 - Article
C2 - 14606568
AN - SCOPUS:0141529847
VL - 22
SP - 1103
EP - 1106
JO - Journal of Ultrasound in Medicine
JF - Journal of Ultrasound in Medicine
SN - 0278-4297
IS - 10
ER -