Collagen corneal shields enhance penetration of topical prednisolone acetate

M. R. Sawusch, Terrence O'Brien, S. A. Updegraff

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

We used an animal model to compare the corneal and aqueous penetration of topical prednisolone acetate 1% with and without the presence of a commercially available collagen corneal shield. A significant P < .02) increase in penetration into cornea and aqueous humor at 30 minutes and 120 minutes was found in eyes with a collagen corneal shield in place. Increased concentrations were achieved by soaking the shield in prednisolone acetate for 15 minutes prior to application.

Original languageEnglish
Pages (from-to)625-628
Number of pages4
JournalJournal of Cataract and Refractive Surgery
Volume15
Issue number6
StatePublished - Jan 1 1989
Externally publishedYes

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Collagen
Aqueous Humor
Cornea
Animal Models
prednisolone acetate

ASJC Scopus subject areas

  • Ophthalmology

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Collagen corneal shields enhance penetration of topical prednisolone acetate. / Sawusch, M. R.; O'Brien, Terrence; Updegraff, S. A.

In: Journal of Cataract and Refractive Surgery, Vol. 15, No. 6, 01.01.1989, p. 625-628.

Research output: Contribution to journalArticle

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