Cognitive impairments associated with early Parkinson's disease

Bonnie Levin, Maria Llabre, W. J. Weiner

Research output: Contribution to journalArticle

219 Scopus citations

Abstract

We administered a battery of cognitive tests to 41 recently diagnosed Parkinson patients and 41 controls to assess the early neuropsychological changes associated with Parkinson's disease (PD). Parkinson subjects did as well as controls on tasks assessing attention and select language and visuospatial measures. However, PD subjects did significantly worse on embedded figures, facial recognition, proverbs, and verbal and figural memory measures, and made more perseverative responses on a set shifting tasks. A discriminant function of measures of proverbs, embedded figures, and memory accounted for 22% of the variance between groups. These data suggest that the cognitive changes in early PD are more pervasive than originally described and may reflect the onset of a more widespread pathologic process.

Original languageEnglish
Pages (from-to)557-561
Number of pages5
JournalNeurology
Volume39
Issue number4
StatePublished - Jan 1 1989

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ASJC Scopus subject areas

  • Neuroscience(all)

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