Cognitive impairment in the schizophrenia spectrum: What is the evidence for similarity to schizophrenia?

Margaret M. McClure, Gayle Zegarelli, Christopher R. Bowie, Vivian Mitropoulou, Larry J. Siever, Philip D. Harvey

Research output: Contribution to journalReview article

Abstract

Cognitive dysfunction is a core component of schizophrenia and is strongly related to functional outcome. Schizotypal personality disorder (SPD) appears closely linked to schizophrenia in terms of biology, phenomenology, outcome, and treatment response. Individuals with SPD demonstrate a similar pattern of cognitive deficits, albeit with less severity in most areas, to individuals with schizophrenia, with core impairments in working memory, context processing, and processing capacity. The validity of the SPD cognitive profile is thus discussed in terms of these areas of impairment that are as great as those in schizophrenia, which lends support to the relationship between schizophrenia and SPD.

Original languageEnglish (US)
Pages (from-to)128-133
Number of pages6
JournalCurrent Psychosis and Therapeutics Reports
Volume4
Issue number3
DOIs
StatePublished - Sep 1 2006
Externally publishedYes

ASJC Scopus subject areas

  • Phychiatric Mental Health
  • Psychiatry and Mental health

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