Cognitive-Behavioral Therapy for Adherence and Depression (CBT-AD) in type 2 diabetes

Jeffrey S. Gonzalez, Lauren A. McCarl, Deborah J. Wexler, Enrico Cagliero, Linda Delahanty, Tiffany D. Soper, Valerie Goldman, Robert Knauz, Steven A. Safren

Research output: Contribution to journalArticle

27 Scopus citations


Depression is one of the most common psychological problems among individuals with diabetes, and is associated with worse treatment adherence and clinical outcomes. As part of a program of treatment research aimed at integrating interventions for depression and treatment nonadherence, five depressed patients with suboptimally controlled type 2 diabetes were treated with 10-12 sessions of individual cognitive-behavioral therapy for adherence and depression (CBT-AD) in a case-series design. The intervention was delivered in a hospital setting by a collaborative team consisting of a psychologist, a nurse educator, and a dietitian. Post-treatment, all participants demonstrated a decrease in depression severity and demonstrated improvements in diabetes self-care. Four of the five demonstrated improved glycemic control. These preliminary results provide evidence for the acceptability, feasibility, and potential utility of CBT-AD for patients with type 2 diabetes and depression.

Original languageEnglish (US)
Pages (from-to)329-343
Number of pages15
JournalJournal of Cognitive Psychotherapy
Issue number4
StatePublished - 2010
Externally publishedYes


  • Adherence
  • CBT
  • Compliance
  • Depression
  • Diabetes

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Clinical Psychology
  • Psychiatry and Mental health

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    Gonzalez, J. S., McCarl, L. A., Wexler, D. J., Cagliero, E., Delahanty, L., Soper, T. D., Goldman, V., Knauz, R., & Safren, S. A. (2010). Cognitive-Behavioral Therapy for Adherence and Depression (CBT-AD) in type 2 diabetes. Journal of Cognitive Psychotherapy, 24(4), 329-343.