Cognitive and motor correlates of everyday functioning in early Huntington's disease

J. C. Rothlind, F. W. Bylsma, C. Peyser, S. E. Folstein, J. Brandt

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

The present study documents the prevalence of deficits in the ability to carry out a variety of activities of daily living in early Huntington's disease (HD), along with the associated neuropsychological and motor deficits. Eighty patients with HD were assessed with the Huntington's Disease-Activities of Daily Living Questionnaire (HD-ADL). Sixty-seven patients also completed a comprehensive assessment of cognitive and voluntary motor functioning and chorea. The latter measures were correlated with HD-ADL total score and with most HD-ADL items, but not with those items dealing with marital and family relationship adjustment. Findings suggest that psychomotor speed and the ability to regulate attention may be particularly important determinants of everyday functioning in mild HD. Consistent with previously reported observations, this appears to be true even after accounting for individual differences in the severity of chorea and voluntary motor impairment.

Original languageEnglish
Pages (from-to)194-199
Number of pages6
JournalJournal of Nervous and Mental Disease
Volume181
Issue number3
StatePublished - Jan 1 1993

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Huntington Disease
Activities of Daily Living
Chorea
Aptitude
Social Adjustment
Family Relations
Marriage
Individuality
Cross-Sectional Studies

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Rothlind, J. C., Bylsma, F. W., Peyser, C., Folstein, S. E., & Brandt, J. (1993). Cognitive and motor correlates of everyday functioning in early Huntington's disease. Journal of Nervous and Mental Disease, 181(3), 194-199.

Cognitive and motor correlates of everyday functioning in early Huntington's disease. / Rothlind, J. C.; Bylsma, F. W.; Peyser, C.; Folstein, S. E.; Brandt, J.

In: Journal of Nervous and Mental Disease, Vol. 181, No. 3, 01.01.1993, p. 194-199.

Research output: Contribution to journalArticle

Rothlind, JC, Bylsma, FW, Peyser, C, Folstein, SE & Brandt, J 1993, 'Cognitive and motor correlates of everyday functioning in early Huntington's disease', Journal of Nervous and Mental Disease, vol. 181, no. 3, pp. 194-199.
Rothlind JC, Bylsma FW, Peyser C, Folstein SE, Brandt J. Cognitive and motor correlates of everyday functioning in early Huntington's disease. Journal of Nervous and Mental Disease. 1993 Jan 1;181(3):194-199.
Rothlind, J. C. ; Bylsma, F. W. ; Peyser, C. ; Folstein, S. E. ; Brandt, J. / Cognitive and motor correlates of everyday functioning in early Huntington's disease. In: Journal of Nervous and Mental Disease. 1993 ; Vol. 181, No. 3. pp. 194-199.
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