Cognition in schizophrenia: Impairments, determinants, and functional importance

Christopher R. Bowie, Philip D. Harvey

Research output: Contribution to journalReview article

202 Scopus citations

Abstract

Recent findings support and add to earlier findings of cognitive dysfunction in schizophrenia. Deficits across neurocognitive domains such as attention, working memory, language skills, and executive functioning tend to be moderate, with the most pronounced deficits found in verbal learning and memory. All these neurocognitive domains are related to adaptive and social skills, with executive functions and verbal learning and memory showing more variance across more domains than other neurocognitive variables. Negative symptoms and neurocognitive domains, although correlated, are distinct and have differential pathways of change with treatment. General psychopathology symptoms, such as depression and anxiety, may become important treatment targets as strategies are developed for translating cognitive enhancement to real-world functional performance.

Original languageEnglish (US)
Pages (from-to)613-633
Number of pages21
JournalPsychiatric Clinics of North America
Volume28
Issue number3 SPEC. ISS.
DOIs
StatePublished - Sep 2005
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health

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