Coexisting choroidal neovascularization and active retinochoroiditis—an uncommon presentation of ocular toxoplasmosis

Sharat Hegde, Nidhi Relhan, Avinash Pathengay, Abhishek Bawdekar, Himadri Choudhury, Animesh Jindal, Harry W. Flynn

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Background: Choroidal neovascularization during the active stage of Toxoplasma retinochoroiditis is an uncommon clinical presentation. The authors retrospectively reviewed medical charts of patients with coexisting choroidal neovascular membrane and active Toxoplasma retinochoroiditis. Findings: Three patients presented with coexisting choroidal neovascular membrane and active Toxoplasma retinochoroiditis. All lesions had adjacent subretinal hemorrhage. The diagnosis was confirmed based on clinical presentation, fundus fluorescein angiography (FFA), and optical coherence tomography (OCT) findings. The patients were managed with a combination of treatments including intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF), oral anti-Toxoplasma treatment, and oral corticosteroids. In all patients, the retinitis lesion resolved in 6 weeks and the coexisting choroidal neovascular membrane resolved over 6 to 12 weeks. Conclusions: Recurrences in Toxoplasma retinochoroiditis are common as satellite lesions adjacent to an old atrophic scar. Coexisting choroidal neovascularization with active Toxoplasma retinochoroiditis is an important presentation and should be suspected in the presence subretinal hemorrhage and managed with a combination of anti-Toxoplasma treatment and intravitreal anti-VEGF.

Original languageEnglish (US)
Article number22
JournalJournal of Ophthalmic Inflammation and Infection
Volume5
Issue number1
DOIs
StatePublished - Dec 23 2015
Externally publishedYes

Keywords

  • Anti-vascular endothelial growth factor (anti-VEGF)
  • Choroidal neovascular membrane
  • Toxoplasma retinochoroiditis

ASJC Scopus subject areas

  • Ophthalmology
  • Infectious Diseases

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