Coexistence of primary antiphospholipid syndrome and protein S deficiency in a Hispanic man with ischemic stroke

Yolanda Reyes-Iglesias, Arturo A. Ortiz, Dario M. Goitía, Rafael Meléndez

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The primary antiphospholipid syndrome and protein S deficiency are known hypercoagulable states predisposing to ischemic strokes. The pathogenesis of those hypercoagulable states has been independently studied and, recently, interaction between them has been proposed. A 48-year-old Hispanic man had generalized seizures 5 months after the acute onset of a left middle cerebral artery infract. He had a strong family history of strokes. After evaluation for cardiology, rheumatologic, hematologic and metabolic etiologies for strokes, anticardiolipin antibodies and protein S deficiency were detected. Cerebral angiography was normal. First degree relatives were evaluated and screened for these conditions. Lupus anticoagulant was detected in a sister who reported a transient hemisensory deficit. None of the relatives studied had clinical or laboratory criteria for collagen vascular deseases. Coexistence of the primary antiphospholipid syndrome and protein S deficiency, two known prothombotic states, has rarely been reported in Hispanic adults in association with ischemic stroke.

Original languageEnglish
Pages (from-to)296-298
Number of pages3
JournalSouthern Medical Journal
Volume91
Issue number3
StatePublished - May 30 1998
Externally publishedYes

Fingerprint

Protein S Deficiency
Antiphospholipid Syndrome
Hispanic Americans
Stroke
Lupus Coagulation Inhibitor
Anticardiolipin Antibodies
Cerebral Angiography
Middle Cerebral Artery
Cardiology
Blood Vessels
Siblings
Seizures
Collagen

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Reyes-Iglesias, Y., Ortiz, A. A., Goitía, D. M., & Meléndez, R. (1998). Coexistence of primary antiphospholipid syndrome and protein S deficiency in a Hispanic man with ischemic stroke. Southern Medical Journal, 91(3), 296-298.

Coexistence of primary antiphospholipid syndrome and protein S deficiency in a Hispanic man with ischemic stroke. / Reyes-Iglesias, Yolanda; Ortiz, Arturo A.; Goitía, Dario M.; Meléndez, Rafael.

In: Southern Medical Journal, Vol. 91, No. 3, 30.05.1998, p. 296-298.

Research output: Contribution to journalArticle

Reyes-Iglesias, Y, Ortiz, AA, Goitía, DM & Meléndez, R 1998, 'Coexistence of primary antiphospholipid syndrome and protein S deficiency in a Hispanic man with ischemic stroke', Southern Medical Journal, vol. 91, no. 3, pp. 296-298.
Reyes-Iglesias, Yolanda ; Ortiz, Arturo A. ; Goitía, Dario M. ; Meléndez, Rafael. / Coexistence of primary antiphospholipid syndrome and protein S deficiency in a Hispanic man with ischemic stroke. In: Southern Medical Journal. 1998 ; Vol. 91, No. 3. pp. 296-298.
@article{2ce5b0b03c4c4572bf0032bfe04516e5,
title = "Coexistence of primary antiphospholipid syndrome and protein S deficiency in a Hispanic man with ischemic stroke",
abstract = "The primary antiphospholipid syndrome and protein S deficiency are known hypercoagulable states predisposing to ischemic strokes. The pathogenesis of those hypercoagulable states has been independently studied and, recently, interaction between them has been proposed. A 48-year-old Hispanic man had generalized seizures 5 months after the acute onset of a left middle cerebral artery infract. He had a strong family history of strokes. After evaluation for cardiology, rheumatologic, hematologic and metabolic etiologies for strokes, anticardiolipin antibodies and protein S deficiency were detected. Cerebral angiography was normal. First degree relatives were evaluated and screened for these conditions. Lupus anticoagulant was detected in a sister who reported a transient hemisensory deficit. None of the relatives studied had clinical or laboratory criteria for collagen vascular deseases. Coexistence of the primary antiphospholipid syndrome and protein S deficiency, two known prothombotic states, has rarely been reported in Hispanic adults in association with ischemic stroke.",
author = "Yolanda Reyes-Iglesias and Ortiz, {Arturo A.} and Goit{\'i}a, {Dario M.} and Rafael Mel{\'e}ndez",
year = "1998",
month = "5",
day = "30",
language = "English",
volume = "91",
pages = "296--298",
journal = "Southern Medical Journal",
issn = "0038-4348",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Coexistence of primary antiphospholipid syndrome and protein S deficiency in a Hispanic man with ischemic stroke

AU - Reyes-Iglesias, Yolanda

AU - Ortiz, Arturo A.

AU - Goitía, Dario M.

AU - Meléndez, Rafael

PY - 1998/5/30

Y1 - 1998/5/30

N2 - The primary antiphospholipid syndrome and protein S deficiency are known hypercoagulable states predisposing to ischemic strokes. The pathogenesis of those hypercoagulable states has been independently studied and, recently, interaction between them has been proposed. A 48-year-old Hispanic man had generalized seizures 5 months after the acute onset of a left middle cerebral artery infract. He had a strong family history of strokes. After evaluation for cardiology, rheumatologic, hematologic and metabolic etiologies for strokes, anticardiolipin antibodies and protein S deficiency were detected. Cerebral angiography was normal. First degree relatives were evaluated and screened for these conditions. Lupus anticoagulant was detected in a sister who reported a transient hemisensory deficit. None of the relatives studied had clinical or laboratory criteria for collagen vascular deseases. Coexistence of the primary antiphospholipid syndrome and protein S deficiency, two known prothombotic states, has rarely been reported in Hispanic adults in association with ischemic stroke.

AB - The primary antiphospholipid syndrome and protein S deficiency are known hypercoagulable states predisposing to ischemic strokes. The pathogenesis of those hypercoagulable states has been independently studied and, recently, interaction between them has been proposed. A 48-year-old Hispanic man had generalized seizures 5 months after the acute onset of a left middle cerebral artery infract. He had a strong family history of strokes. After evaluation for cardiology, rheumatologic, hematologic and metabolic etiologies for strokes, anticardiolipin antibodies and protein S deficiency were detected. Cerebral angiography was normal. First degree relatives were evaluated and screened for these conditions. Lupus anticoagulant was detected in a sister who reported a transient hemisensory deficit. None of the relatives studied had clinical or laboratory criteria for collagen vascular deseases. Coexistence of the primary antiphospholipid syndrome and protein S deficiency, two known prothombotic states, has rarely been reported in Hispanic adults in association with ischemic stroke.

UR - http://www.scopus.com/inward/record.url?scp=0031959769&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031959769&partnerID=8YFLogxK

M3 - Article

C2 - 9521377

AN - SCOPUS:0031959769

VL - 91

SP - 296

EP - 298

JO - Southern Medical Journal

JF - Southern Medical Journal

SN - 0038-4348

IS - 3

ER -