Patients on long term renal dialysis suffer a greater incidence of occlusive arterial disease. Because this latter observation has been extended to recipients of renal allografts, it was decided to investigate 69 long term survivors (out of 115) as regards these complications. Coagulation studies were carried out on all 69 survivors with renal allografts. Fibrinogen levels were significantly raised. Factor VIII activity was increased in 7 of the 11 patients studied. Six long term survivors of renal allografts demonstrated arterial thrombotic phenomena. The onset of the thrombotic episode occurred at a relatively young age. It is considered that the hypercoagulable state may contribute to the observed increased tendency towards arterial thrombotic phenomena.
|Original language||English (US)|
|Number of pages||4|
|Journal||South African Medical Journal|
|State||Published - Dec 1 1976|
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