Abstract
While the previous review of CNS-IRIS in the HIV-infected patient on highly active antiretroviral therapy (Part 1) dealt with an overview of the biology, pathology, and neurologic presentation of this condition and a discussion of the atypical imaging findings in PML-IRIS and cryptococcal meningitis-IRIS due to the robust inflammatory response, the current review (Part 2) discusses the imaging findings in other commonly encountered organisms seen in association with CNS-IRIS, namely, VZV, CMV, HIV, Candida organisms, Mycobacterium tuberculosis, and Toxoplasma gondii. Also described is the imaging appearance of CNS-IRIS when not associated with a particular organism. Recognition of these imaging findings will give credence to the diagnosis of CNS-IRIS and will allow the clinician to institute changes in medical management, if necessary, so that immune reconstitution and improved patient outcome can occur with time.
Original language | English (US) |
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Pages (from-to) | 1308-1318 |
Number of pages | 11 |
Journal | American Journal of Neuroradiology |
Volume | 34 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2013 |
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology