Closure of the abdominal wall with acellular dermal allograft in intestinal transplantation

R. S. Mangus, C. A. Kubal, A. J. Tector, J. A. Fridell, K. Klingler, R. M. Vianna

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Loss of abdominal domain is a common problem in intestinal transplantation. Several surgical options are available perioperatively for abdominal wall reconstruction. This study reports the management and complications for intestinal transplant patients with abdominal wall closure either primarily or with foreign material. This single center study reviews the records of intestinal transplant patients between 2004 and 2010. Study outcomes included reoperation for dehiscence, hernia or enterocutaneous fistula. There were 37 of 146 patients (25%) who required implantation of foreign material at transplant. Of these 37, 30 (81%) had implantation of acellular dermal allograft (ADA) and 7 (19%) implantation of another mesh. Perioperative dehiscence was rare with 2/109 (2%) for primary closure, 0/30 (0%) for ADA and 1/7 (14%) for other mesh. There were 12/146 (8%) patients who underwent ventral hernia repair: primary closure 7/109 (6%), ADA 3/30 (10%) and other mesh 2/7 (28%). There were 4/146 (3%) patients who required surgery for enterocutaneous fistulas: 2/109 (2%) primary closure, 1/30 (3%) ADA and 1/7 (14%) synthetic mesh. Abdominal wall reconstruction with ADA biologic mesh provides an expeditious means of performing a tension-free closure of the fascial layer after intestinal transplantation with complications similar to those seen for primary closure.

Original languageEnglish (US)
Pages (from-to)S55-S59
JournalAmerican Journal of Transplantation
Issue numberSUPPL 4
StatePublished - 2012
Externally publishedYes


  • Abdominal domain
  • Abdominal wall reconstruction
  • Acellular dermal allograft
  • Biologic mesh
  • Intestinal transplantation

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)


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