Clofazimine enteropathy: A rare and underrecognized complication of mycobacterial therapy

Winnie Szeto; Monica T. Garcia-Buitrago; Lilian Abbo; Joseph D. Rosenblatt; Baharak Moshiree; Michele I. Morris

doi:10.1093/ofid/ofw004

Clofazimine enteropathy: A rare and underrecognized complication of mycobacterial therapy

Winnie Szeto, Monica T. Garcia-Buitrago, Lilian Abbo, Joseph D. Rosenblatt, Baharak Moshiree, Michele I. Morris

Research output: Contribution to journal › Article

7 Scopus citations

Abstract

Clofazimine-induced crystal-storing histiocytosis is a rare complication of treatment previously reported in dermatology literature as a complication of leprosy therapy. We report a case of disseminated Mycobacterium abscessus requiring treatment with high-dose oral clofazimine resulting in enteropathy in a patient who presented with abdominal pain, malnutrition, and melena.

Original language	English (US)
Article number	ofw004
Journal	Open Forum Infectious Diseases
Volume	3
Issue number	3
DOIs	https://doi.org/10.1093/ofid/ofw004
State	Published - 2016

Keywords

Clofazimine
Clofazimine-induced enteropathy
Crystal storing histiocytosis enteropathy
Mycobacterium abscessus
Petechial hemorrhage

ASJC Scopus subject areas

Oncology
Clinical Neurology

Access to Document

10.1093/ofid/ofw004

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Szeto, W., Garcia-Buitrago, M. T., Abbo, L., Rosenblatt, J. D., Moshiree, B., & Morris, M. I. (2016). Clofazimine enteropathy: A rare and underrecognized complication of mycobacterial therapy. Open Forum Infectious Diseases, 3(3), [ofw004]. https://doi.org/10.1093/ofid/ofw004

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