Clinicopathologic study of idiopathic macular pucker in children and young adults

William E Smiddy, R. G. Michels, H. D. Gilbert, W. R. Green

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Clinically significant idiopathic macular pucker was observed in 11 patients aged 30 years or younger. In these patients, the tissue was well defined and fibrous in appearance, in contrast to the thin, cellophane appearance that is typical of macular pucker in elderly patients. Vitrectomy and epiretinal membrane peeling were performed in each case. Visual acuity improved after surgery in seven cases and worsened in one case, and follow-up data was not obtained in three cases. Recurrent membranes were noted in four cases, two of which detached spontaneously. Ultrastructural studies were performed on the removed specimens in each case. Myofibroblasts, myoblastic differentiation of retinal pigment epithelial cells and fibrous astrocytes, and new collagen formation were more common than in idiopathic macular pucker in older patients. The clinical and ultrastructural features of juvenile macular pucker reflect more rapidly changing, contractile tissue compared with the usually more quiescent features in series involving older patients.

Original languageEnglish
Pages (from-to)232-236
Number of pages5
JournalRetina
Volume12
Issue number3
StatePublished - Sep 30 1992
Externally publishedYes

Fingerprint

Young Adult
Cellophane
Epiretinal Membrane
Retinal Pigments
Myofibroblasts
Vitrectomy
Astrocytes
Visual Acuity
Collagen
Epithelial Cells
Membranes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Smiddy, W. E., Michels, R. G., Gilbert, H. D., & Green, W. R. (1992). Clinicopathologic study of idiopathic macular pucker in children and young adults. Retina, 12(3), 232-236.

Clinicopathologic study of idiopathic macular pucker in children and young adults. / Smiddy, William E; Michels, R. G.; Gilbert, H. D.; Green, W. R.

In: Retina, Vol. 12, No. 3, 30.09.1992, p. 232-236.

Research output: Contribution to journalArticle

Smiddy, WE, Michels, RG, Gilbert, HD & Green, WR 1992, 'Clinicopathologic study of idiopathic macular pucker in children and young adults', Retina, vol. 12, no. 3, pp. 232-236.
Smiddy WE, Michels RG, Gilbert HD, Green WR. Clinicopathologic study of idiopathic macular pucker in children and young adults. Retina. 1992 Sep 30;12(3):232-236.
Smiddy, William E ; Michels, R. G. ; Gilbert, H. D. ; Green, W. R. / Clinicopathologic study of idiopathic macular pucker in children and young adults. In: Retina. 1992 ; Vol. 12, No. 3. pp. 232-236.
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