Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal

A. M. Maguire, William E Smiddy, S. K. Nanda, R. G. Michels, Z. de la Cruz, W. R. Green

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Recurrent epiretinal membranes (ERMs) causing macular pucker developed after surgical removal in seven eyes and were subsequently removed. A specimen was available for electron microscopic study from four of the seven primary operations and all seven of the repeat operations. The diagnostic associations for the primary cases included retinal holes or tears (four eyes), trauma, inflammation (one eye each). In one eye the membrane was idiopathic. The primary and recurrent ERM specimens contained similar cell types and structural characteristics but were not identical. No one cell type predominated in either primary or recurrent ERM. Compared with studies of idiopathic ERMs, myofibroblasts were present with increased frequency in recurrent membranes. Fibrocytes, fibrous astrocytes, and retinal pigment epithelial cells were also present in most specimens. Other features of both the primary and recurrent ERM specimens included the presence of cells with myoblastic differentiation, fragments of internal limiting membrane, new collagen, and nerve fiber elements.

Original languageEnglish
Pages (from-to)213-222
Number of pages10
JournalRetina
Volume10
Issue number3
StatePublished - Nov 14 1990

Fingerprint

Epiretinal Membrane
Retinal Perforations
Membranes
Retinal Pigments
Myofibroblasts
Nerve Fibers
Astrocytes
Collagen
Epithelial Cells
Electrons
Inflammation
Wounds and Injuries

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Maguire, A. M., Smiddy, W. E., Nanda, S. K., Michels, R. G., de la Cruz, Z., & Green, W. R. (1990). Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal. Retina, 10(3), 213-222.

Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal. / Maguire, A. M.; Smiddy, William E; Nanda, S. K.; Michels, R. G.; de la Cruz, Z.; Green, W. R.

In: Retina, Vol. 10, No. 3, 14.11.1990, p. 213-222.

Research output: Contribution to journalArticle

Maguire, AM, Smiddy, WE, Nanda, SK, Michels, RG, de la Cruz, Z & Green, WR 1990, 'Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal', Retina, vol. 10, no. 3, pp. 213-222.
Maguire AM, Smiddy WE, Nanda SK, Michels RG, de la Cruz Z, Green WR. Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal. Retina. 1990 Nov 14;10(3):213-222.
Maguire, A. M. ; Smiddy, William E ; Nanda, S. K. ; Michels, R. G. ; de la Cruz, Z. ; Green, W. R. / Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal. In: Retina. 1990 ; Vol. 10, No. 3. pp. 213-222.
@article{2a9aca34dc784a5494fd3cebfded9880,
title = "Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal",
abstract = "Recurrent epiretinal membranes (ERMs) causing macular pucker developed after surgical removal in seven eyes and were subsequently removed. A specimen was available for electron microscopic study from four of the seven primary operations and all seven of the repeat operations. The diagnostic associations for the primary cases included retinal holes or tears (four eyes), trauma, inflammation (one eye each). In one eye the membrane was idiopathic. The primary and recurrent ERM specimens contained similar cell types and structural characteristics but were not identical. No one cell type predominated in either primary or recurrent ERM. Compared with studies of idiopathic ERMs, myofibroblasts were present with increased frequency in recurrent membranes. Fibrocytes, fibrous astrocytes, and retinal pigment epithelial cells were also present in most specimens. Other features of both the primary and recurrent ERM specimens included the presence of cells with myoblastic differentiation, fragments of internal limiting membrane, new collagen, and nerve fiber elements.",
author = "Maguire, {A. M.} and Smiddy, {William E} and Nanda, {S. K.} and Michels, {R. G.} and {de la Cruz}, Z. and Green, {W. R.}",
year = "1990",
month = "11",
day = "14",
language = "English",
volume = "10",
pages = "213--222",
journal = "Retina",
issn = "0275-004X",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Clinicopathologic correlation of recurrent epiretinal membranes after previous surgical removal

AU - Maguire, A. M.

AU - Smiddy, William E

AU - Nanda, S. K.

AU - Michels, R. G.

AU - de la Cruz, Z.

AU - Green, W. R.

PY - 1990/11/14

Y1 - 1990/11/14

N2 - Recurrent epiretinal membranes (ERMs) causing macular pucker developed after surgical removal in seven eyes and were subsequently removed. A specimen was available for electron microscopic study from four of the seven primary operations and all seven of the repeat operations. The diagnostic associations for the primary cases included retinal holes or tears (four eyes), trauma, inflammation (one eye each). In one eye the membrane was idiopathic. The primary and recurrent ERM specimens contained similar cell types and structural characteristics but were not identical. No one cell type predominated in either primary or recurrent ERM. Compared with studies of idiopathic ERMs, myofibroblasts were present with increased frequency in recurrent membranes. Fibrocytes, fibrous astrocytes, and retinal pigment epithelial cells were also present in most specimens. Other features of both the primary and recurrent ERM specimens included the presence of cells with myoblastic differentiation, fragments of internal limiting membrane, new collagen, and nerve fiber elements.

AB - Recurrent epiretinal membranes (ERMs) causing macular pucker developed after surgical removal in seven eyes and were subsequently removed. A specimen was available for electron microscopic study from four of the seven primary operations and all seven of the repeat operations. The diagnostic associations for the primary cases included retinal holes or tears (four eyes), trauma, inflammation (one eye each). In one eye the membrane was idiopathic. The primary and recurrent ERM specimens contained similar cell types and structural characteristics but were not identical. No one cell type predominated in either primary or recurrent ERM. Compared with studies of idiopathic ERMs, myofibroblasts were present with increased frequency in recurrent membranes. Fibrocytes, fibrous astrocytes, and retinal pigment epithelial cells were also present in most specimens. Other features of both the primary and recurrent ERM specimens included the presence of cells with myoblastic differentiation, fragments of internal limiting membrane, new collagen, and nerve fiber elements.

UR - http://www.scopus.com/inward/record.url?scp=0025015530&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025015530&partnerID=8YFLogxK

M3 - Article

VL - 10

SP - 213

EP - 222

JO - Retina

JF - Retina

SN - 0275-004X

IS - 3

ER -