Clinicopathologic correlation of pigmented epiretinal membranes

George M. Cherfan, William E. Smiddy, Ronald G. Michels, Zenaida de la Cruz, C. P. Wilkinson, W. Richard Green

Research output: Contribution to journalArticle

22 Scopus citations


We performed Clinicopathologic correlation on ten surgically removed pigmented epiretinal membranes causing macular pucker. All cases occurred in eyes with existing retinal holes or tears, including eight cases of macular pucker after previous retinal detachment. These cases probably represented a limited form of proliferative vitreoretinopathy. All membranes contained pigment epithelial cells with polarity, basement membrane, and melanosomes. Cytoplasmic melanin granules accounted for the clinical feature of pigmentation in these eyes.

Original languageEnglish (US)
Pages (from-to)536-545
Number of pages10
JournalAmerican journal of ophthalmology
Issue number5
StatePublished - Nov 15 1988
Externally publishedYes


ASJC Scopus subject areas

  • Ophthalmology

Cite this

Cherfan, G. M., Smiddy, W. E., Michels, R. G., de la Cruz, Z., Wilkinson, C. P., & Green, W. R. (1988). Clinicopathologic correlation of pigmented epiretinal membranes. American journal of ophthalmology, 106(5), 536-545.