Clinicopathologic correlation of chorioretinitis sclopetaria

Sander Dubovy, David L. Guyton, W. Richard Green

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Purpose: To report the clinicopathologic features in the eye of a patient who sustained a traumatic chorioretinal rupture from a gunshot wound to the orbit, chorioretinitis sclopetaria, with clinical follow up of more than 20 years. Methods: The patient was studied ophthalmoscopically and by fluorescein angiography after the trauma and was seen intermittently thereafter. The eyes were obtained postmortem; sections of the central portion of the right eye, including the macula and optic nerve head, and the inferior cap were examined by light microscopy. Results: Histopathologic study of the right eye showed partial loss of the nerve fiber and ganglion cell layers in the macular area, temporal peripapillary and macular loss of the photoreceptors with hypertrophy and hyperplasia of the retinal pigment epithelium, an epiretinal membrane, and three defects in Bruch's membrane. Inferiorly, there was a 5mm defect in choroid, Bruch's membrane, and retina. These structures were replaced by a loose and dense fibrous connective tissue. The sclera and a long posterior ciliary nerve remained intact. A thin fibrovascular tissue from the choroid extended into the subretinal space where it was covered by retinal pigment epithelium and thickened basement membrane in the posterior aspect of the inferior lesion. Marked hemiatrophy of the optic nerve was present. Conclusion: The clinicopathologic features of chorioretinitis sclopetaria include direct traumatic chorioretinal rupture followed by marked fibrovascular proliferation with variable replacement of choroid and retina with no retinal detachment. Posteriorly, indirect macular the retina and choroid, epiretinal membrane formation, loss of photoreceptors, and marked hemiatrophy of the optic nerve were present.

Original languageEnglish
Pages (from-to)510-520
Number of pages11
JournalRetina
Volume17
Issue number6
StatePublished - Dec 1 1997
Externally publishedYes

Fingerprint

Chorioretinitis
Choroid
Bruch Membrane
Epiretinal Membrane
Retina
Retinal Pigment Epithelium
Optic Nerve
Rupture
Gunshot Wounds
Sclera
Fluorescein Angiography
Optic Disk
Orbit
Retinal Detachment
Nerve Fibers
Basement Membrane
Ganglia
Connective Tissue
Hypertrophy
Hyperplasia

Keywords

  • Blunt trauma
  • Chorioretinitis sclopetaria
  • Choroidal rupture

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Dubovy, S., Guyton, D. L., & Green, W. R. (1997). Clinicopathologic correlation of chorioretinitis sclopetaria. Retina, 17(6), 510-520.

Clinicopathologic correlation of chorioretinitis sclopetaria. / Dubovy, Sander; Guyton, David L.; Green, W. Richard.

In: Retina, Vol. 17, No. 6, 01.12.1997, p. 510-520.

Research output: Contribution to journalArticle

Dubovy, S, Guyton, DL & Green, WR 1997, 'Clinicopathologic correlation of chorioretinitis sclopetaria', Retina, vol. 17, no. 6, pp. 510-520.
Dubovy S, Guyton DL, Green WR. Clinicopathologic correlation of chorioretinitis sclopetaria. Retina. 1997 Dec 1;17(6):510-520.
Dubovy, Sander ; Guyton, David L. ; Green, W. Richard. / Clinicopathologic correlation of chorioretinitis sclopetaria. In: Retina. 1997 ; Vol. 17, No. 6. pp. 510-520.
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