Clinical recognition and evaluation of peptic ulcer disease

S. D. Rosen, A. I. Rogers

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

When a patient has epigastric pain that worsens 1 to 3 hours after meals, the possibility of peptic ulcer disease should be considered. Completely typical clinical presentations in patients younger than age 50 justify empirical therapy when no physical or laboratory findings suggest a mimicking disorder. Esophagogastroduodenoscopy should be undertaken when response to therapy is incomplete, symptoms recur quickly, or dyspeptic symptoms present for the first time in a patient older than age 50. When gastric ulcers are diagnosed radiographically, endoscopy and biopsy at multiple sites should be done to exclude malignant disease. Intractable duodenal ulcers may necessitate endoscopic biopsy of antral and duodenal mucosa to rule out an associated Helicobacter pylori infection, which may modify therapeutic approaches. Zollinger-Ellison syndrome is rare but should be suspected when ulcer disease presents atypically or aggressively or in families. Diagnosis is not difficult to confirm.

Original languageEnglish
Pages (from-to)42-47+51+55
JournalPostgraduate Medicine
Volume88
Issue number5
StatePublished - Jan 1 1990
Externally publishedYes

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Peptic Ulcer
Zollinger-Ellison Syndrome
Digestive System Endoscopy
Biopsy
Helicobacter Infections
Stomach Ulcer
Duodenal Ulcer
Helicobacter pylori
Endoscopy
Ulcer
Meals
Mucous Membrane
Therapeutics
Pain

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Rosen, S. D., & Rogers, A. I. (1990). Clinical recognition and evaluation of peptic ulcer disease. Postgraduate Medicine, 88(5), 42-47+51+55.

Clinical recognition and evaluation of peptic ulcer disease. / Rosen, S. D.; Rogers, A. I.

In: Postgraduate Medicine, Vol. 88, No. 5, 01.01.1990, p. 42-47+51+55.

Research output: Contribution to journalArticle

Rosen, SD & Rogers, AI 1990, 'Clinical recognition and evaluation of peptic ulcer disease', Postgraduate Medicine, vol. 88, no. 5, pp. 42-47+51+55.
Rosen SD, Rogers AI. Clinical recognition and evaluation of peptic ulcer disease. Postgraduate Medicine. 1990 Jan 1;88(5):42-47+51+55.
Rosen, S. D. ; Rogers, A. I. / Clinical recognition and evaluation of peptic ulcer disease. In: Postgraduate Medicine. 1990 ; Vol. 88, No. 5. pp. 42-47+51+55.
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