Clinical presentation of fibrodysplasia ossificans progressiva: Pitfalls in diagnosis

Christopher J. Magryta, Chris J. Kligora, H. Thomas Temple, Rajesh K. Malik

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A patient presented with a rapidly growing mass in the cervicothoracic paraspinous region. Associated clinical and radiographic skeletal abnormalities and histopathologic findings showing mild to moderate proliferation of spindle cells in a myxoid stroma led to the diagnosis of fibrodysplasia ossificans progressiva. Recognizing the clinical features of this disease is important and should avoid the need for obtaining tissue to make the diagnosis, because performing a biopsy may be particularly morbid in these patients.

Original languageEnglish (US)
Pages (from-to)539-543
Number of pages5
JournalJournal of Pediatric Hematology/Oncology
Issue number6
StatePublished - 1999
Externally publishedYes


  • Fibrodysplasia ossificans progressiva
  • Paraspinous mass

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology


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