Clinical, physiopathological and dietetic aspects of metabolic syndrome

F. Leonetti, G. Lacobellis, A. Zappaterreno, U. Di Mario

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Hypertriglyceridaemia, diabetes, hypertension and obesity are the "deadly quartet" indicating a syndrome at high risk for cardiovascular disease for which, in 1998, WHO proposed the definition of Metabolic Syndrome, related to an elevated degree of insulin resistance. Treatment will often include behavioural changes that reduce body weight and increase physical activity. A high-carbohydrate/low-fat diet with complex carbohydrates and mainly unsaturated fat is recommended. Replacing refined grain products and potatoes with minimally processed plant-based foods such as whole grains, fruit, and vegetables, and reducing the intake of high glycaemic load beverages may offer a simple strategy for reducing the incidence of coronary heart disease.

Original languageEnglish (US)
Pages (from-to)S134-S139
JournalDigestive and Liver Disease
StatePublished - Sep 2002
Externally publishedYes


  • Diabetes
  • Insulin
  • Metabolic syndrome
  • Obesity

ASJC Scopus subject areas

  • Gastroenterology


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