Abstract
Theoretically, the airway circulation can regulate the absorption of inhaled drugs, redistribute inhaled drugs within the respiratory tract, and influence the distribution of systemic drugs to the airway. Some of these functions of the airway circulation have been verified experimentally, but not in human subjects. Since pharmacological manipulation of airway blood flow could have therapeutic implications in airway disease, the development of new methods to measure airway blood flow noninvasively in human subjects is needed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 19-23 |
| Number of pages | 5 |
| Journal | Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung |
| Volume | 9 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1996 |
Keywords
- aerosol therapy
- airway blood flow
- airway disease
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine