Clinical perspectives: Role of the airway circulation in drug therapy

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Theoretically, the airway circulation can regulate the absorption of inhaled drugs, redistribute inhaled drugs within the respiratory tract, and influence the distribution of systemic drugs to the airway. Some of these functions of the airway circulation have been verified experimentally, but not in human subjects. Since pharmacological manipulation of airway blood flow could have therapeutic implications in airway disease, the development of new methods to measure airway blood flow noninvasively in human subjects is needed.

Original languageEnglish (US)
Pages (from-to)19-23
Number of pages5
JournalJournal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung
Issue number1
StatePublished - Jan 1 1996


  • aerosol therapy
  • airway blood flow
  • airway disease

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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