Clinical features of adenosquamous lung carcinoma in 127 patients

K. S. Sridhar, M. J. Bounassi, W. Raub, Stephen P Richman

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

There has been increased recognition of adenosquamous lung carcinoma since the 1982 modification of World Health Organization (WHO) histologic criteria. However, data on clinical features of this histologic subtype were nonexistent. Medical records of 127 patients with adenosquamous lung carcinoma were reviewed to determine the clinical features, namely, age, race, sex, smoking history, asbestos exposure, symptoms present at the time of diagnosis, stage, treatments, and survival. The age distribution was: <40 yr, 3%; 40 to 49, 17%; 50 to 59, 28%; 60 to 69, 32%; 70 to 79, 18%; ≥80, 2%. Men constituted 72%, and 90% were smokers. Four smokers had documented asbestos exposure. The symptoms in order of decreasing frequency were cough, weight loss, expectoration, anorexia, chest pain, dyspnea, weakness, hemophysis, pneumonia, fever, nausea, vomiting, dizziness, and chills. Stage could be ascertained in 120 (95%) patients. Local stage constituted 10%, regional constituted 30%, and distant constituted 60%. Local stage had the best survival, with a projected 5-yr survival of 62%. Median survivals in regional and distant stages were 8 and 4 months, respectively. Symptoms of adenosquamous lung carcinoma were similar to other histologies. Most patients present in regional or distant stages. Local-stage patients had a good long-term survival after surgical excision of the tumor.

Original languageEnglish
Pages (from-to)19-23
Number of pages5
JournalAmerican Review of Respiratory Disease
Volume142
Issue number1
StatePublished - Jan 1 1990

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Adenosquamous Carcinoma
Lung
Survival
Asbestos
Chills
Age Distribution
Anorexia
Dizziness
Chest Pain
Cough
Dyspnea
Nausea
Vomiting
Medical Records
Weight Loss
Pneumonia
Histology
Fever
Smoking
History

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Clinical features of adenosquamous lung carcinoma in 127 patients. / Sridhar, K. S.; Bounassi, M. J.; Raub, W.; Richman, Stephen P.

In: American Review of Respiratory Disease, Vol. 142, No. 1, 01.01.1990, p. 19-23.

Research output: Contribution to journalArticle

Sridhar, K. S. ; Bounassi, M. J. ; Raub, W. ; Richman, Stephen P. / Clinical features of adenosquamous lung carcinoma in 127 patients. In: American Review of Respiratory Disease. 1990 ; Vol. 142, No. 1. pp. 19-23.
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