Clinical evaluation of the patient with jaundice

Research output: Contribution to journalArticle

Abstract

Jaundice, with and without hepatobiliary damage, has a wide spectrum of causes. In the initial evaluation, fractionation of the bilirubin facilitates differential diagnosis. Unconjugated hyperbilirubinemia most often is the result of pigment overload or Gilbert's disease. Most patients with jaundice seen by the clinician have underlying hepatobiliary disease. Liver biopsy usually establishes the etiology of hepatocellular forms of jaundice. In patients with cholestasis, visualization of the biliary tree by either transhepatic or endoscopic retrograde cholangiopancreatography provides the most direct means of differentiating mechanical biliary obstruction from intrahepatic cholestasis.

Original languageEnglish
Pages (from-to)334-343
Number of pages10
JournalActa Gastro-Enterologica Belgica
Volume42
Issue number9-10
StatePublished - Dec 1 1979
Externally publishedYes

Fingerprint

Jaundice
Gilbert Disease
Intrahepatic Cholestasis
Hyperbilirubinemia
Endoscopic Retrograde Cholangiopancreatography
Cholestasis
Biliary Tract
Bilirubin
Differential Diagnosis
Biopsy
Liver

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Clinical evaluation of the patient with jaundice. / Schiff, Eugene R.

In: Acta Gastro-Enterologica Belgica, Vol. 42, No. 9-10, 01.12.1979, p. 334-343.

Research output: Contribution to journalArticle

@article{5f6323e46cc24800963e4e34a675f15c,
title = "Clinical evaluation of the patient with jaundice",
abstract = "Jaundice, with and without hepatobiliary damage, has a wide spectrum of causes. In the initial evaluation, fractionation of the bilirubin facilitates differential diagnosis. Unconjugated hyperbilirubinemia most often is the result of pigment overload or Gilbert's disease. Most patients with jaundice seen by the clinician have underlying hepatobiliary disease. Liver biopsy usually establishes the etiology of hepatocellular forms of jaundice. In patients with cholestasis, visualization of the biliary tree by either transhepatic or endoscopic retrograde cholangiopancreatography provides the most direct means of differentiating mechanical biliary obstruction from intrahepatic cholestasis.",
author = "Schiff, {Eugene R}",
year = "1979",
month = "12",
day = "1",
language = "English",
volume = "42",
pages = "334--343",
journal = "Acta Gastro-Enterologica Belgica",
issn = "0001-5644",
publisher = "Universa Press",
number = "9-10",

}

TY - JOUR

T1 - Clinical evaluation of the patient with jaundice

AU - Schiff, Eugene R

PY - 1979/12/1

Y1 - 1979/12/1

N2 - Jaundice, with and without hepatobiliary damage, has a wide spectrum of causes. In the initial evaluation, fractionation of the bilirubin facilitates differential diagnosis. Unconjugated hyperbilirubinemia most often is the result of pigment overload or Gilbert's disease. Most patients with jaundice seen by the clinician have underlying hepatobiliary disease. Liver biopsy usually establishes the etiology of hepatocellular forms of jaundice. In patients with cholestasis, visualization of the biliary tree by either transhepatic or endoscopic retrograde cholangiopancreatography provides the most direct means of differentiating mechanical biliary obstruction from intrahepatic cholestasis.

AB - Jaundice, with and without hepatobiliary damage, has a wide spectrum of causes. In the initial evaluation, fractionation of the bilirubin facilitates differential diagnosis. Unconjugated hyperbilirubinemia most often is the result of pigment overload or Gilbert's disease. Most patients with jaundice seen by the clinician have underlying hepatobiliary disease. Liver biopsy usually establishes the etiology of hepatocellular forms of jaundice. In patients with cholestasis, visualization of the biliary tree by either transhepatic or endoscopic retrograde cholangiopancreatography provides the most direct means of differentiating mechanical biliary obstruction from intrahepatic cholestasis.

UR - http://www.scopus.com/inward/record.url?scp=0018642450&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018642450&partnerID=8YFLogxK

M3 - Article

C2 - 554406

AN - SCOPUS:0018642450

VL - 42

SP - 334

EP - 343

JO - Acta Gastro-Enterologica Belgica

JF - Acta Gastro-Enterologica Belgica

SN - 0001-5644

IS - 9-10

ER -