Clinical course of vitreomacular traction managed initially by observation

Jonathan H. Tzu, Vishak J. John, Harry W Flynn, William E Smiddy, Jared R. Jackson, Blake A. Isernhagen, Adam Carver, Robert Leonard, Homayoun Tabandeh, David S. Boyer, Maria H. Berrocal, Mihoko Suzuki, K. Bailey Freund, Jeffrey G. Gross

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

BACKGROUND AND OBJECTIVE: To investigate the clinical course and outcomes of patients with vitreomacular traction (VMT) managed initially by observation. PATIENTS AND METHODS: This noncomparative case series included patients with a diagnosis of VMT based on clinical symptoms and findings on spectral-domain optical coherence tomography (SD-OCT) between 2005 and 2014. VMT was documented using a standardized grading system based on the degree of distortion of the foveal contour. Data were collected at five retina clinics using standardized collection forms. Visual acuity, changes in SD-OCT findings, and timing of the release of VMT as seen on SD-OCT were recorded. RESULTS: The study included 230 eyes of 185 patients. Mean age was 72.5 years, and mean follow-up was 32 months. At baseline, VMT grading was grade 1 in 92 eyes (40%), grade 2 in 118 eyes (51.3%), and grade 3 in 20 eyes (8.7%). By last follow-up, spontaneous release of VMT occurred in 73 eyes (31.7%). Spontaneous release of VMT occurred at a mean of 18 months (median: 10.9 months) after initial visit. Mean logMAR best corrected visual acuity (BCVA) was 0.28 (20/55) (range: 20/20 to 20/400) at baseline and 0.25 (20/51) (range: 20/20 to 20/400) at last follow-up. Pars plana vitrectomy was performed in 10 eyes (4.1%) for macular hole (six eyes) and increased VMT (four eyes); BCVA was at least 20/40 in eight of the 10 eyes at last follow-up. CONCLUSION: Patients with VMT generally had a favorable clinical course when managed initially by observation. Spontaneous release of VMT occurred in approximately one-third of patients. At last follow-up, pars plana vitrectomy was performed in fewer than 5% of patients.

Original languageEnglish (US)
Pages (from-to)571-576
Number of pages6
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume46
Issue number5
DOIs
StatePublished - May 1 2015

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ASJC Scopus subject areas

  • Ophthalmology
  • Surgery

Cite this

Tzu, J. H., John, V. J., Flynn, H. W., Smiddy, W. E., Jackson, J. R., Isernhagen, B. A., Carver, A., Leonard, R., Tabandeh, H., Boyer, D. S., Berrocal, M. H., Suzuki, M., Freund, K. B., & Gross, J. G. (2015). Clinical course of vitreomacular traction managed initially by observation. Ophthalmic Surgery Lasers and Imaging Retina, 46(5), 571-576. https://doi.org/10.3928/23258160-20150521-09