Clinical assessment of axis I psychiatric morbidity in chronic epilepsy

A multicenter investigation

Jana E. Jones, Brace P. Hermann, John J. Barry, Frank Gilliam, Andres M Kanner, Kimford J. Meador

Research output: Contribution to journalArticle

179 Citations (Scopus)

Abstract

This study characterizes the rate of current Axis I DSM-IV disorders using a brief standardized psychiatric interview procedure, the Mini International Neuropsychiatric Interview (v5.0) (MINI), and determined the validity of MINI diagnoses of current depressive episodes to the research standard (Structured Clinical Interview for DSM-IV Disorders [SCID]). One hundred seventy-four patients with chronic epilepsy from five tertiary medical centers were interviewed using the MINI and the mood disorders module of the SCID. Current Axis I disorders were evident in one-half the sample (49%), with prevalent anxiety (30.4%) and mood (21.8%) disorders. Major depressive episode was the most common individual diagnosis (17.2%). Concordance was high between the MINI and SCID for diagnoses of current depression, especially for major depression. Of those with current major depression, less than one-half were treated with antidepressant medications. Current Axis I DSM-IV diagnoses can be effectively and accurately identified in clinical settings using shorter standardized psychiatric interview techniques. Issues regarding recognition and treatment of psychiatric morbidity in epilepsy are discussed. copyright

Original languageEnglish (US)
Pages (from-to)172-179
Number of pages8
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume17
Issue number2
DOIs
StatePublished - Jan 1 2005
Externally publishedYes

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Psychiatry
Epilepsy
Diagnostic and Statistical Manual of Mental Disorders
Interviews
Morbidity
Depression
Mood Disorders
Antidepressive Agents
Anxiety
Research

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Clinical assessment of axis I psychiatric morbidity in chronic epilepsy : A multicenter investigation. / Jones, Jana E.; Hermann, Brace P.; Barry, John J.; Gilliam, Frank; Kanner, Andres M; Meador, Kimford J.

In: Journal of Neuropsychiatry and Clinical Neurosciences, Vol. 17, No. 2, 01.01.2005, p. 172-179.

Research output: Contribution to journalArticle

Jones, Jana E. ; Hermann, Brace P. ; Barry, John J. ; Gilliam, Frank ; Kanner, Andres M ; Meador, Kimford J. / Clinical assessment of axis I psychiatric morbidity in chronic epilepsy : A multicenter investigation. In: Journal of Neuropsychiatry and Clinical Neurosciences. 2005 ; Vol. 17, No. 2. pp. 172-179.
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